Folia Medica Indonesiana
ISSN 0303-7932
Vol. 46 / No. 4 / Published : 2010-10
Order : 10, and page :282 - 285
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Original Article :
Comparison of maternal zinc level in term pregnancy associated with premature rupture of membranes in normal pregnancy
Author :
- Muh. Nadir Abdullah *1
- Moh. Fauzi*2
- Department of Obstetrics & Gynecology, Faculty of Medicine, Airlangga University, Dr Soetomo Hospital
- Department of Obstetrics & Gynecology, Faculty of Medicine, Airlangga University, Dr Soetomo Hospital
Abstract :
The purpose of this study was to determine maternal zinc levels, whether there is any difference between term pregnancy associated with premature rupture of membranes and normal pregnancy. This was an analytic observational study using comparative, cross sectional design. Sample comprised 40 mothers with term pregnancy and vaginal birth at Dr. Soetomo Hospital, consisting of 20 term pregnancy with premature rupture of membranes (PROM) and 20 term pregnancy without complications. We used venous blood specimens, colostrum and head hair. Specimens were prepared to be homogeneous solution for analysis. Levels of zinc in the specimen were determined using Atomic absorption Spectrophotometry. Blood zinc levels in term pregnancy with PROM (4.33 + 1.21 ppm) were significantly lower than in term normal pregnancy (5.20 + 1.33 ppm), with p = 0.036. Zinc content of colostrum (5.86 + 3.51 ppm vs 6.95 + 3.77 ppm) and head hair (254.85 + 167.45 ppm vs. 348.78 + 228.17 ppm) was not significantly different from the second group (p> 0.05). In conclusion, blood zinc levels in term pregnancy with PROM was lower than that in normal pregnancy. Hair zinc concentration of colostrum and the head did not differ between the two groups.
Keyword :
maternal zinc status, premature rupture of membranes (PROM), term pregnancy,
References :
Aggett PJ,(1985) Trace element and human pregnancy and lactation. In: Chandra RK (ed). Trace Element in Nutrition of Children New York : Nestle Nutrition, Vavey/Raven Press
French JI and McGregor JA,(1996) The Seminar in Perinatology : Pathobiology of Premature Rupture of Membranes - : Saunders Company
Nendrosuwito N,(1999) Pedoman Pemeriksaan Logam Berat dalam Spesimen Manusia dengan Metoda Spektrofotometer dan Spektrofotometer Serapan Atom Jakarta : Departemen Kesehatan RI
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