UNIVERSITAS AIRLANGGA



Detail Article

Folia Medica Indonesiana

ISSN 0303-7932

Vol. 50 / No. 1 / Published : 2014-01

Order : 6, and page :25 - 29

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Original Article :

Correlation between n-terminal pro-brain natriuretic peptide level with dyastolicfunction echocardiography parameter in acute coronary syndrome

Author :

  1. Fouzal Aswad*1
  2. Muhammad Aminuddin*2
  3. Jusak Nugraha*3
  1. Zainoel Abidin General Hospital
  2. Dosen Fakultas Kedokteran
  3. Dosen Fakultas Kedokteran

Abstract :

Acute coronary syndromes is one of the most common cause of death. Echocardiography for the evaluation of left ventricular (LV)function has become an important component in risk assessment. the usefulness of various biochemical variables has beenrecognized and N-Terminal Pro-Brain Natriuretic Peptide (NT-proBNP) has been proven to be an important prognostic marker andreleased as a respons of wall stress and myocyte stretch. Elevated NT-proBNP concentrations at admission in the setting of ACS areassociated with poor prognosis, including increased mortality, \development of CHF, and recurrent ischemic events. This study AimFor analyze correlation between serum level of NT-proBNP and echocardiography parameters left ventricle diastolic function inAcute Coronary Syndrome. by means we measured plasma level of NTproBNP 34 Acute Coronary Syndrome patients in EmergencyDepartement and ICCU Dr.Soetomo Hospital. RELIA TM Immunoassay Diagnostic Instrument (SSJ-2) kit was used to measured NTproBNPconcentrations with ELISA method, on 1 and 6 hours after admission and echocardiography was perform on admission todetermine LV dysfunction. There were 34 subject, women and men and mean age was 35-79 years old. The mean of peak NTproBNP,1 and 6 hours after admission consecutively were 2040,3062 ± 4169,89471 pg/ml and 2683,3376 ± 4190,66055 pg/ml. Themean peak E/A 0,8676 ± 0,26825 and DT 238,24 ± 39,134. There was no correlation between NTproBNP concentration on 1 and 6hours after admision and peak E/A. There was a correlation between plasma NT-proBNP level and DT on echocardiography in acutecoronary syndromes(FMI 2014;50:25-29)

Keyword :

Acute Coronary Syndrome, NT-proBNP, echocardiography,


References :

Anand SS, Islam S, Rosengren A, Franzosi MG, Steyn K, Yusufali AH, Keltai M, Diaz R, Rangarajan S, Y,(2008) Risk factors for myocardial infarction in women and men: insights from the INTERHEART study - : Eur Heart J

Bassand JP, Hamm CW, Ardissino D, Boersma E, Budaj A, Fernández-Avilés F, Fox KA, Hasdai D, Ohman ,(2007) Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes - : Eur Heart J





Archive Article

Cover Media Content

Volume : 50 / No. : 1 / Pub. : 2014-01
  1. Genetic Mutation Profile Of Gyra And Parc Gene In Ciprofloxacin-resistance Pseudomonas Aeruginosa
  2. The Depression Profile Of People Living With Hiv/aids (plwha) Receiving Antiretroviral Treatment In Dr. Soetomo Hospital Surabaya
  3. Agreement Between Estimated Apolipoprotein B-100 Concentration And Apolipoprotein B-100 Concentration Measured By Immunoturbidimetric Method
  4. Er, Pr, And Her-2/neu Profile On Young Breast Carcinoma Patients
  5. Correlation Between Heart Type Fatty Acid Binding Protein Serum Level And Soluble St2 In Acute Coronary Syndrome Patients
  6. Correlation Between N-terminal Pro-brain Natriuretic Peptide Level With Dyastolicfunction Echocardiography Parameter In Acute Coronary Syndrome
  7. Correlation Between E/vp And E/e’ In Left Ventricular Filling Pressure Measurement Among Patients With Dilated Cardiomyopathy
  8. Changes In Platelet Count, Mean Platelet Volume, Platelet Distribution Width, And Plateletcrit In Pulmonary Tuberculosis Severity
  9. Microbial Pattern And Antibiotic Susceptibility Test In Semen Gresik Hospital 2012
  10. Diagnostic Values Of Immature Granulocytes, Eosinopenia And I/t Ratio In Detection Of Early Onset Neonatal Sepsis In Neonates With Bacterial Infection Risk
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  13. Mean Score Of Cervical Pedicle Angle To Midline And Inferior End Plate In Adult Using Multi Sliced Computed Tomography

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