UNIVERSITAS AIRLANGGA



Detail Article

Folia Medica Indonesiana

ISSN 0303-7932

Vol. 43 / No. 1 / Published : 2007-01

Order : 2, and page :7 - 12

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Original Article :

Effect of loranthaceae daendropthoe species infusion on serum transaminase level and hepatic necrosis in rats

Author :

  1. Arifa Mustika*1
  2. Roostantia Indrawati*2
  3. Ratna Sofaria Munir*3
  1. Department of Medical Pharmacy Airlangga University School of Medicine
  2. Department of Medical Pharmacy Airlangga University School of Medicine
  3. Department of Medical Pharmacy Airlangga University School of Medicine

Abstract :

Loranthaceae daendropthoe is a herbal preparation which has been shown as cell antiproliferant and traditionally used as anticancer. The infusion of the plant is given via oral route, which is subsequently absorbed by gastrointestinal and metabolised in liver. Liver performs many essential functions, including the production of bile, regulation of plasma proteins and glucose as well as biotransformation of drugs and toxins. This study examined whether Loranthaceae daendropthoe makes liver tissue damage in animal model. Mouse as animal models were divided into two groups, the control group was given with aquademineralisata and treatment group was given with infusion of Loranthaceae daendropthoe. Serum transaminase, specific marker of hepatocellular necrosis and the histology of mouse liver were studied 17 days after the treatment with plant infusion. Data of serum transaminase and histology were comparedbetween treatment and control groups. The result suggested that the infusion of Loranthaceae aendropthoe did not cause liver diseases.

Keyword :

Loranthaceae daendropthoe, infusion, serum transaminase, hepatic necrosis, SGOT, SGPT,


References :

Asmino,(1995) Pengalaman Pribadi dengan Pengobatan Alternatif Surabaya : Airlangga University Press

JD Birkett,(1979) Fundamental of Clinical Pharmacology, Drug Biotransformation no info : Medical Progress

VMP Carrero,(2004) Liver Pediatrics no info : no info

EO Pineiro,(2004) Liver Pediatrics no info : no info

M Carrascosa,(1997) Arcabose-induced acute severe heapatotoxicity no info : The Lancet

F Pascual,(1997) Arcabose-induced acute severe heapatotoxicity no info : The Lancet

S Aresti,(1997) Arcabose-induced acute severe heapatotoxicity no info : The Lancet

Departemen Kesehatan Republik Indonesia,(2000) Acuan Sediaan Herbal Jakarta : Departemen Kesehatan Republik Indonesia

EG Giannini,(2005) Liver enzyme alteration: a guide for clinicians no info : Canadian Medical Association Journal

R Testa,(2005) Liver enzyme alteration: a guide for clinicians no info : Canadian Medical Association Journal

Savarino,(2005) Liver enzyme



Archive Article

Cover Media Content

Volume : 43 / No. : 1 / Pub. : 2007-01
  1. Serum P53 Protein And Total Lymphocyte Profile In Sepsis Patients Treated With Ciprofloxacin And Cefotaxime
  2. Effect Of Loranthaceae Daendropthoe Species Infusion On Serum Transaminase Level And Hepatic Necrosis In Rats
  3. Glucose 6 Phosphate Dehydrogenase (g6pd) Deficiency In Bad Pregnancy History In St. Vincentius A Paulo Catholic Hospital, Surabaya
  4. Heparin Effect On Vegf And Egfr After Deep Second And Third Degree Burns In Rattus Novergicus Strain Wistar
  5. Examination Of Oxldl Serum Level As The Prognosis Of Acute Thrombotic Ischemic Stroke
  6. Mental Changes In Parkinson's Disease A Study Of Fifty Patients
  7. Microscopic Picture And Water Content In Dentin Analysis Of Bonding Agent Bond To Dentin Surface An Evaluation Of Various Humidity
  8. Localization Of Plasmodium Falciparum Asexual Stage Antigen By Mouse Immune Sera
  9. Description Of Urinary Retention In Women A Retrospective Study In Dr Soetomo Hospital Surabaya
  10. Review Article: The Potential Intervention On Apoptosis And Cell Cycle Activity In Rheumatoid Arthritis
  11. Review Article: The Role Of Microglia As Prime Component Of Cns Immune System In Acute And Chronic Neuroinflammation
  12. Review Article And Clinical Experience: A Novel “two-in-one” Drug Fixed Combination Of Ros And Met Its Roles On Ir, Prediabetes, Mets, T2dm And Cvd

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