UNIVERSITAS AIRLANGGA



Detail Article

Folia Medica Indonesiana

ISSN 0303-7932

Vol. 48 / No. 3 / Published : 2012-07

Order : 5, and page :115 - 120

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Original Article :

Essential oil extract of citrus aurantifolia l. has better antibacterial effect than sulfur towards staphylococcus epidermidis

Author :

  1. Rebekah Juniati Setiabudi*1
  2. Ratna Sofaria Munir*2
  3. Jeffery Ali Nurdin*3
  1. Dosen Fakultas Kedokteran
  2. Dosen Fakultas Kedokteran
  3. Mahasiswa Fakultas Kedokteran

Abstract :

The use of sulfur as the cure of most common skin disease is well known around the world. But its effectiveness is quite not reliable some disease such as for acne vulgaris, the multifactorial skin disease. One of the cause for acne growth is bacterial infection, including Propionibacterium acnes and Staphylococcus epidermidis. Meanwhile, some research suggests that essential oil of Citrus aurantifolia L., which is usually used for cooking, have the antibacterial activity. The purpose of this study is to compare the antibacterial activity of sulfur and essential oil of Citrus aurantifolia L. toward the acne causing bacteria, Staphylococcus epidermidis. This research was laboratory experimental study. The essential oil extract of Citrus aurantifolia L. was made with Water and Steam Distillation while we use sulfur in the form of powder. This extract was examined in Staphylococcus epidermidis. Experimental method is serial dilution. Result was analyzed descriptively with Minimum Inhibitory Concentration (MIC). The examination in each bacterium was repeated 5 times. The result showed that essential oil extract of Citrus aurantifolia L. has ability to inhibit the growth of Staphylococcus epidermidis at concentration 25%. While the ability of sulfur to inhibit the growth of Staphylococcus epidermidis on 50% or no inhibition at all (visual observation). From result repetition in 5 times, gram positive is more stable rather than gram negative. In conclusion, the essential oil extract of Citrus aurantifolia L. has better antibacterial effect than sulfur towards Staphylococcus epidermidis. MIC for essential oil of Citrus aurantifolia L. at 25% while for MIC sulfur at 50% (FMI 2012;48:115-120).

Keyword :

antibacterial, Citrus hystrix DC, sulfur, Staphylococcus epidermidis,


References :

Guenther E,(1987) The Essential Oils Minyak Atsiri Jilid I Jakarta : UI-Press

Marks R, Plunkett A, Merlin K, Jenner N,(1999) Atlas of Common Skin Diseases in Australia Melbourne : Department of Dermatology St Vincent’s Hospital





Archive Article

Cover Media Content

Volume : 48 / No. : 3 / Pub. : 2012-07
  1. In Vitro Intraerythrocytic Antimalarial Activity Of Akar Kuning (arcangelisia Flava (l.) Merr.) Stem Aqueous Extract In Plasmodium Falciparum
  2. In Vitro Antimalarial Activity Of Belimbing Wuluh (averrhoa Bilimbi) Leaves Extract On Plasmodium Falciparum
  3. Effect Of Earthworms (lumbricus Sp.) Extract Antibacterial Activity Against The Bacteria Salmonella Typhii
  4. In Vitro Antibacterial Activities Of Commercial Probiotic Drinks Against Salmonella Typhii
  5. Essential Oil Extract Of Citrus Aurantifolia L. Has Better Antibacterial Effect Than Sulfur Towards Staphylococcus Epidermidis
  6. Benzalkonium Chloride And Pine Oil-containing Cleaning Fluid Is Not Effective Against Pseudomonas Aeruginosa
  7. Mrsa-carrier Detection In Semester-1 Students Of Medical Doctor Program, Faculty Of Medicine, Airlangga University, Surabaya, Class 2009
  8. Preterm Birth And The Affecting Factors In Dr. Soetomo Hospital, Surabaya, Indonesia
  9. Effect Of Type-2 Diabetes Mellitus On Cataract Incidence Rate At Ophthalmology Outpatient Clinic, Dr Soetomo Hospital, Surabaya