UNIVERSITAS AIRLANGGA



Detail Article

Folia Medica Indonesiana

ISSN 0303-7932

Vol. 50 / No. 3 / Published : 2014-07

Order : 4, and page :148 - 152

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Original Article :

The overview of macrophage, mast cell, and lymphocyte activity in the efficacy distinction of pain reduction for dry and wet cupping therapies

Author :

  1. Imam Subadi*1
  2. Hening Laswati Putra*2
  3. Indrayuni Lukitra Wardhani*3
  1. Dosen Fakultas Kedokteran
  2. Dosen Fakultas Kedokteran
  3. Dosen Fakultas Kedokteran

Abstract :

There are two methods in cupping therapy, they are dry cupping and wet cupping. Both methods are used to reduce pain; howeverthe effectiveness of each method has not known yet. The aims of this research were to compare the effectiveness in pain reliefbetween dry cupping therapy and wet cupping therapy and to find out the overview of macrophage, mast cell and lymphocyteactivity. This study was a randomized controlled trial post test only design. Thirty-two white rats obtained, Wistar type, weight 300 ±50 grams, age 3 months, divided into 4 groups. Group 1 (n = 8) consists normal rats, group 2 (n = 8) contains rats with inducedpain, group 3 (n = 8) consists rats with induced pain and dry cupping therapy while group 4 (n = 8) consists rats with induced painand wet cupping therapy. Pain variable was obtained by measuring pain threshold reaction time using hot plate. The amount ofmacrophage, mast cell and lymphocyte were measured with HE stain under the light microscope. Statistical analysis was usingoneway Anova with SPSS 17 device. Pain threshold reaction time in negative control group is 10.66 ± 2.71 secs, positive controlgroup 11.78 ± 3.58 secs, dry cupping therapy group 16.93 ± 3.63 secs and wet cupping therapy group 22.81 ± 6.34 secs. Wetcupping therapy reduce pain more than dry cupping therapy (p < 0,05) significantly. Therefore, wet cupping therapy is moreeffective than dry cupping therapy. Macrophage is the most dominant immune cell in wet cupping therapy. (FMI 2014;50:148-152)

Keyword :

cupping therapy, pain, macrophage,


References :

Ahmadi A, Schwebel DC, Rezaei M,(2008) The efficacy of wet-cupping in the treatment of tension and migraine headache 36, 37-44 : Am J Chin Med

Brattwall M, Turan I, Jakobsson J,(2010) Musculoskeletal pain: prescription of NSAID and weak opioid by primary health care physicians in Sweden 2004-2008 - a retrospective patient record review 3, 131-135 : J Pain Res





Archive Article

Cover Media Content

Volume : 50 / No. : 3 / Pub. : 2014-07
  1. Heavy Metal Contamination May Have A Role In Negative Correlation Between Seafood Consumption And Visuo-motor Development Of 1-3 Year-old Children In Subdistrict Bulak, Surabaya
  2. Detection Of Gyra Gene Mutation Region In Fluoroquinolone Resistant Mycobacterium Tuberculosis Isolate From Surabaya Indonesia
  3. Intravenous Vitamin C Administration Decreases Nitric Oxide Serum Level In Severe Burn Injury
  4. The Overview Of Macrophage, Mast Cell, And Lymphocyte Activity In The Efficacy Distinction Of Pain Reduction For Dry And Wet Cupping Therapies
  5. Effectiveness Of Fosfomycin On Prevention Of Surgical Site Infection Of Closed Brain Injury Patients After Craniotomy In Emergency Unit Dr. Soetomo Hospital
  6. Soot Particulate Matter Exposure Increases Interleukin 6 Levels In The Mechanism Of Cardiovascular Disorders
  7. Electric Shock Increases Vcam And Mcp In Mice Endothelial Blood Vessel
  8. Magnesium And Potassium Parenteral Supplementation Does Not Produce Significant Effect On Magnesium And Potassium Serum Level Of Cervical Cancer Patients Receiving Cisplatin Chemotherapy
  9. Effect Of G-csf On Anc Level In All (acute Lymphoblastic Leukemia) Patient With Neutropenia And Febrile Neutropenia During Chemotherapy
  10. Comparative Effectiveness Of Paracetamol And Metamizol As Antipyretics In Patients With Moderate And Severe Brain Injury In Dr. Soetomo Hospital, Surabaya
  11. Analysis Of Complicated Factors Affecting Therapy Effectiveness In Urinary Tract Infections
  12. In Infant With Acute Diarrhea, Nutritional Status Has Correlation With Dehydration Degree, But Not With Mother’s Education And Breastfeeding
  13. The Use Of Antibiotics In Patients With Urinary Tract Infection

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