Folia Medica Indonesiana
ISSN 0303-7932
Vol. 51 / No. 1 / Published : 2015-01
Order : 10, and page :53 - 58
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Original Article :
The use of fetal free dna as non-invasive techniques on sex identification
Author :
- Agung Sosiawan*1
- Ahmad Yudianto*2
- Human Genetic Laboratory, Institute of Tropical Disease, Universitas Airlangga
- Dosen Fakultas Kedokteran
Abstract :
Urgent use of samples based on cell free fetal on forensic cases in the future will be inevitable need. Unborn child given thecomplexity of the cases related to abortus provocatus identification or other criminal cases that are predicted to continue to rise. Toovercome these problems, a practical solution for forensic DNA experts is the use non-invasive techniques with samples derived fromcell free fetus. the use of this material is expected to help the process of forensic personal identification to assist law enforcement inIndonesia. This study using free fetal DNA to detect the sex of a fetus at 8 weeks gestation or more, where the use of ultrasound isstill not possible. The result of this study is cell free fetal DNA in the maternal circulation promising new hope for the benefitforensic identification. It enable forensic examination in cases of paternity can be done in the future. (FMI 2015;51:53-58)
Keyword :
fetal cell free, non-invasive technique, unborn child identification,
References :
Lo YM, Tein MS, Lau TK, Haines CJ, Leung TN, Poon PM, Wainscoat JS, Johnson PJ, Chang AM, Hjelm NM ,(1998) Quantitative analysis of fetal DNA in maternal plasma and serum: implications for noninvasive prenatal diagnosis 62, 768-775 : Am J Hum Genet
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