The Indonesian Journal of Public Health
ISSN 1829-7005
Vol. 9 / No. 2 / Published : 2013-01
Order : 5, and page :141 - 149
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Original Article :
Pengaruh pemberian probiotik mengandung lactobacillus reuteri terhadap jumlah cd4+ dan status gizi usia lanjut (studi di panti jompo jaga mara pati kabupaten buleleng, bali)
Author :
- Ida Ayu Putu Pertiwi*1
- Mahasiswa Fakultas Kesehatan Masyarakat
Abstract :
ABSTRACT The number of elderly is rapidly increase, including in Indonesia. With aging, comes a reduction in overall health and increased morbidity and mortality due to infectious disease. One of the major cause is the immunity changes with aging including inhibited Cell Mediated Immunity. One of the cells that has important role in Cell Mediated Immunity is CD4+. Giving probiotic containing L. reuteri is expected to stimulate immune function including increase the number of CD4+, which in turn can improve the nutritional status in elderly. The purpose of this study was to analyze the effect of probiotic containing L. reuteri on number of CD4+ and nutritional status in elderly. This study was randomized experimental study using Pre Test Post Test Control Group Design with a double blind treatment. The research population was all health elderly aged 60-80 years old at Panti Jompo Jaga Mara Pati Buleleng, Bali. The samples consist of two groups, treatment and control group, each of the samples in group was 13 elderly. The treatment group were given probiotic tablet each contain 6,5billion L. reuteri for 4 weeks, while the control group given nothing. The result showed that after intervention, there were no differences in number of CD4+ between treatment group and control group with p = 0.290 (α = 0.05). To nutritional status, there were no differences between treatment group and control group with p = 0.317 (α = 0.05). But there are significant differences in morbidity due to infectious disease during supplementation between treatment group and control group with p = 0.030 (α = 0.05). From this research can be concluded that there are no differences in number of CD4+ and nutritional status between treatment group and control group. But there are differences in morbidity due to infectious disease between treatment group and control group. There for, further research needed to determine the effect of probiotic to infectious disease. Keywords: L. reuteri, number of CD4+, nutritional status, elderly
Keyword :
L. reuteri, number of CD4+, nutritional status, elderly,
References :
Brown J.E,(2005) Nutrition Through The Life Cycle USA : Thomson Wadsworth
High K.P,(1998) Alterations of Immune Defense Mechanisms in the Elderly: The Role of Nutrition. sitasi 14 Februari 2010 : http://www.thai-otsuka. co.th/pxnews/0498nl01.htm.
Hughes D.A., Darlington L.G., Bendich A,(2004) Diet and Human Immune Fuction New Jersey : Humana Press
Kementrian Koordinator Bidang Kesejahteraan Rakyat,(2009) Data Usia harapan hidup di Indonesia tahun 2005- 2010 serta persentase penduduk lanjut usia tahun 2005 Jakarta : Kementrian Koordinator Bidang Kesejahteraan Rakyat
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