Jurnal Farmasi dan Ilmu Kefarmasian
ISSN
Vol. 2 / No. 1 / Published : 2015-10
Order : 6, and page :25 - 30
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Original Article :
Aktivitas antibakteri susu probiotik lactobacilli terhadap bakteri penyebab diare (escherichia coli, salmonella typhimurium, vibrio cholerae)
Author :
- Nopriadi Nelintong*1
- Isnaeni*2
- Noor Erma Nasution*3
- Mahasiswa Fakultas Farmasi
- Dosen Fakultas Farmasi
- Dosen Fakultas Farmasi
Abstract :
Lactobacillus plantarum, Lactobacillus casei, and Lactobacillus acidophilus fermented milk were made in single and mixed preparation. Their antibacterial activities were investigated against diarrhea’s bacterial Escherichia coli, Salmonella typhimurium, Vibrio cholera as bacterial test and cyprofloxacine as reference standard by using agar diffusion method. The highest zone of inhibitions produced by L. plantarum and L. casei fermented milk at 9:1 ratio, 12,33 ± 0,07 mm, 12,43 ± 0,29 mm, and 12,32 ± 0,81 mm against Escherichia coli, Salmonella typhimurium, and Vibrio cholera respectively. The highest activity of the combination of L. plantarum and L. casei (9:1) and L. acidophilus was produced at 9:1 ratio, 13,08±0,08 mm, 13,46±0,04 mm, and 13,21±0,02 mm against Escherichia coli, Salmonella typhimurium, and Vibrio cholera respectively. Minimum inhibitory concentration of the combination fermented milk with L. plantarum and L. casei (9:1) and L. acidophilus in ratio 9:1 was 40% against Escherichia coli, Salmonella typhimurium, and Vibrio cholerae.
Keyword :
Lactobacillus plantarum, Lactobacillus casei, Lactobacillus acidophilus, fermented milk, diarrhea’s bacterial,
References :
Afriani,(2010) Pengaruh Penggunaan Starter Bakteri Asam Laktat Lactobacillus plantarum dan Lactobacillus fermentum terhadapTotal Bakteri Asam Laktat, Kadar Asam dan Nilai pH Dadih Susu Sapi Vol. 13, No. 6, p. 279-285 : Jurnal Ilmiah Ilmu-Ilmu Peternakan
Allen SJ, Martinez EG, Gregorio GV, Dans LF,(2011) Probiotics for treating acute infectious diarrhea p. 185 : Sao Paulo Medical Journal
Lourens-Hattingh A, Viljoen BC,(2001) Susu probiotik as probiotic carrier food Vol. 11, p. 1-17 : International Dairy Journal
Tamime AY, Saarela M, Sondergaard AK, Mistry VV, Shah NP,(2005) Production and maintenance of viability of probiotic micro-organisms in dairy products. Di dalam Tamime AY (ed). Probiotic Dairy Products p. 39-72 : Oxford: Blackwell Publishing Ltd.
Anonim,(1995) Farmakope Indonesia, Edisi 4 hal. 891-899 : Direktorat Jenderal Pengawas Obat dan Makanan, Jakarta
Archive Article
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