Jurnal Farmasi dan Ilmu Kefarmasian
ISSN
Vol. 2 / No. 2 / Published : 2015-12
Order : 2, and page :41 - 43
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Original Article :
Identifikasi golongan senyawa dan uji toksisitas akut ekstrak etanol 95 persen daun, kulit batang dan akar pulai (alstonia scholaris (l.) r. br.) terhadap mencit balb/c
Author :
- Jurusan Kimia Fakultas Sains dan Teknologi, UIN Maulana Malik Ibrahim Malang *1
- Jurusan Kimia Fakultas Sains dan Teknologi, UIN Maulana Malik Ibrahim Malang*2
- Ismiyah, F.
- Fauziyah, B.
Abstract :
Recently, Use of traditional medicine derived of plants chosen by the public in treating some kinds of diseases. One of the herbs that have been used by people as a medicine is plant Pulai (Alstonia scholaris (L.) Br.). This study was conducted to learn chemical active ingredients and to make sure that it safe to consumed. In this research, identification of active ingredients and the LD50 value of 95% ethanol extract of the leaves, bark and roots of Pulai was determine. Results of phytochemical test are, 95% ethanol extract of leaves of Pulai give positive results for alkaloids and saponins; 95% ethanol extract of the stem bark Pulai gives positive results for alkaloids, saponins, and terpenoids and 95% ethanol extract of the roots of Pulai gives positive results for alkaloids and terpenoids. LD50 value of 95% ethanol extract of the leaves, bark and roots are > 5.000mg/kg bw indicates that the Pulai extract is practically non-toxic.
Keyword :
Pulai (Alstonia scholaris (L.) R. Br), phytochemical test, toxicity test,
References :
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