UNIVERSITAS AIRLANGGA



Detail Article

VetMedika Jurnal Klinik Veteriner

ISSN 2302-6499

Vol. 1 / No. 1 / Published : 2012-07

Order : 4, and page :15 - 22

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Original Article :

Combined of ampicilline, dextran-40 and dexamethason on the prevention of intra-abdominal adhesions postoperative hysterotomy in cat (fellis catus)

Author :

  1. Ira Sari Yudaniayanti*1
  2. Frans Tito Timora*2
  3. Erni Rosilawati Sabar Iman*3
  1. Departemen Klinik Veteriner Fakultas Kedokteran Hewan
  2. Sarjana Kedokteran Hewan
  3. Departemen Mikrobiologi Fakultas Kedokteran Hewan

Abstract :

The aim of this study was to assess the effects of ampicilline, dextran-40, and dexamethasone as single or combination on prevention of intra-abdominal adhesion formation postoperative hysterotomy  in cat. This research uses 10 female cats, 12-18 months of age, followed randomly divided into five groups: (I) was control group, with no treatment; (II) 100 mg ampicilline in 3 ml aqua pro injection was applied intraperitoneally (IP); (III) ampicilline 100mg/ 3ml aqua pro injection + dextran-40, 20 ml/kg  bw were applied IP; (IV)  ampicilline 100mg/3ml aqua pro injection applied IP + dexamethasone 0,2 ml/ kg bw given intramuscularly (IM); (V) ampicilline 100mg/3ml aqua pro injection + dextran-40, 20 ml/ kgbw were applied IP + dexamethasone 0,2 ml/kg bw, given IM. After all cats were anesthetized, the cats treated laparo-hysterotomy surgery.  All cats underwent a second laparotomy on the postoperative 15th day for  evaluating a possible  intra-abdominal adhesion formation. The Kruskall-Walis test was used to test for differences in the grades of wide and tightnes intra-abdominal adhesion observed in the five groups. The result shows that  a significant difference among five treatment groups (p < 0,05).  The combined of ampicilline, dextran-40, and dexamethasone (P V)  is an effective way to prevent intra-abdominal adhesion.

Keyword :

intra-abdominal adhesion, ampicilline, dextran-40 , dexamethasone, hysterotomy ,


References :

Arin K, MD Greene, PJ Alwayn, Nose V, Flynn E, D Sampson, D Zurakowski, Folkman J, M Puder,(2005) Prevention of intra-abdominal adhesions using the antiangiogenic COX-2 inhibitor celecoxib Philadelphia : Annual Surgery

DiZerega GS, JD Campeau,(1994) Use of instilates to prevent intraperitoneal adhesion:crystalloids and dextran New York : Infertil. Reprod. Med. Clinics N. Am

Emre A, Akin M, Isikgonul I, Yuksel O, Anadol AZ, Cifter C,(2009) Comparison of intraperitoneal honey and sodium hyaluronate-carboxymethylcellulose (SeprafilTM) for the prevention of postoperative intra-abdominal adhesions New York : Clinics

Wang X, Gui C, Zheng Q,(2003) Combined therapy of allantoin, metronidazole, dexamethasone on the prevention of intra-abdominal adhesion in dog and its quantitative analysis : World J Gastroenterol





Archive Article

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Volume : 1 / No. : 1 / Pub. : 2012-07
  1. The Correlation Between Breed And Obesity In Dogs In Surabaya
  2. Histopathology Of Renal Male Rats Of Femoral Fracture With Cissus Quadrangularis Plant Extract And Calcium Carbonate Therapy
  3. Treatment Of Canine Demodecosis In Veterinary Teaching Hospital Faculty Of Veterinary Medicine Airlangga University
  4. Combined Of Ampicilline, Dextran-40 And Dexamethason On The Prevention Of Intra-abdominal Adhesions Postoperative Hysterotomy In Cat (fellis Catus)
  5. Packed Cell Volume Comparison Of Dog Blood Before And After Storage Using Citrate-phosphate-dextrose
  6. Alkaline Phosphatase Blood Levels Before And After Rabbit Mandibula Bones Reconstruction By The Block Of Autograft Decortication And Non Decortication Technique
  7. The Profil Of Intraocular Pressure Using Combination Ketamine-xylazine And Ketamine-midazolam In Rabbit (oryctolagus Cuniculus)
  8. Case Study : Feline Polycystic Kidney Disease

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