UNIVERSITAS AIRLANGGA



Detail Article

VetMedika Jurnal Klinik Veteriner

ISSN 2302-6499

Vol. 3 / No. 2 / Published : 2015-01

Order : 3, and page :9 - 12

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Original Article :

The comparison of wound healing time of staphylococcus aureus infection between the effect of topical treatment of apple cider vinegar and oxytetracycline on mice (mus musculus)

Author :

  1. Yeni Purbowati*1
  2. Erni Rosilawati SI*2
  3. Arimbi*3
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Dosen Fakultas Kedokteran Hewan

Abstract :

This research was conducted to investigate the ability of apple cider vinegar, as traditional medicine for wound healing incision on mice (Mus musculus) were infected by Staphylococcus aureus. Eighteen of three mounth old female mice (Mus musculus) BALB/c strain with 25 gram everage body weight was divided into three group, A, B and C. group A was given treatment with apple cider vinegar, group B was given treatment with Oxytetracycline as antibotic and group C as a control was not given treatmnt. Each treatment was consist of six mice (Mus musculus). The treatment was given topically three times a day. Observation of wound healing was characterized by the exfoliation of the scab and wound closure. The experimental design used in this study was using completely ramdmized design (CRD). The data were analized by Analysis of Variance (ANOVA) and then was followed by Honestly Significant Difference (HSD) test with  significance of 1%. The result showed that the treatment using apple cider vinegar and oxytetracycline affect the healing time of the Staphylococcus aureus wound infection on mice (Mus musculus), amd the treatment indicated that apple cider vinegar showed the best result compared to both antibiotic treatment and control.

Keyword :

apple cider vinegar, Staphylococcus aureus,


References :

Atma, CD,(2014) Efektifitas antibakteri cuka apel varietas Anna produk sendiri dan kemasan terhadap pertumbuhan bakteri Staphylococcus aureus secara in vitro Skripsi : Fakultas Kedokteran Hewan Universitas Airlangga.

Katzung, BG,(2009) Basic and clinical pharmacology. 7th Edition New York : Prentice Hall, Appleton & Lange

Nayak BS, Sandiford S, Maxwell A,(2007) Evaluation of the wound-healing activity of ethanolic extract of morinda citriflora leaf 6(3):351-356 : Evid Based Complement Alternative Medicine

Kormaz A, U Sahiner and M Yurdakok,(2000) Chemical burn caused by topical vinegar application in a newborn infant 17:34-36 : Pediatr Dermatol





Archive Article

Cover Media Content

Volume : 3 / No. : 2 / Pub. : 2015-01
  1. The Comparison Of Wound Healing Time Of Staphylococcus Aureus Infection With Treatment Of Self Produced Apple Cider Vinegar And Commercial Apple Cider Vinegar Topically On Mice (mus Musculus)
  2. The Urolithiasis Incidence In Cats At Veterinary Teaching Hospital Of Faculty Veterinary Medicine Airlangga University In Period 2013-2014
  3. The Comparison Of Wound Healing Time Of Staphylococcus Aureus Infection Between The Effect Of Topical Treatment Of Apple Cider Vinegar And Oxytetracycline On Mice (mus Musculus)
  4. Incidence Of Endometritis In Dairy Cows At Kud Sumber Makmur Ngantang Subdistrict Malang Regency
  5. Case Study: Diaphragmatic Hernia In Cat

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