UNIVERSITAS AIRLANGGA



Detail Article

VetMedika Jurnal Klinik Veteriner

ISSN 2302-6499

Vol. 1 / No. 1 / Published : 2012-07

Order : 7, and page :33 - 38

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Original Article :

The profil of intraocular pressure using combination ketamine-xylazine and ketamine-midazolam in rabbit (oryctolagus cuniculus)

Author :

  1. Ira Sari Yudaniayanti*1
  2. Daud Yusuf*2
  3. M. Zainal Arifin*3
  4. Benjamin Chr. Tehupuring*4
  5. Handayani Tjitro*5
  1. Departemen Klinik Veteriner Fakultas Kedokteran Hewan
  2. Sarjana Kedokteran Hewan
  3. Departemen Klinik Veteriner Fakultas Kedokteran Hewan
  4. Departemen Anatomi Veteriner Fakultas Kedokteran Hewan
  5. Departemen Klinik Veteriner Fakultas Kedokteran Hewan

Abstract :

The purpose of this study was to find out the effect of combining anesthesia ketamine-xylazine and ketamine-midazolam to intraocular pressure in male using Schiotz tenometer. This helps in providing information on the safety of the medicine to rabbits. This study used 14 male rabbits (Oryctolagus cuniculus) age of 5-6 months and body weight of 1,3-2 kg were randomly divided into two treatments using Complete Random Block Design. First treatment (P1), the rabbits were injected with atropine (0,05 mg/kg BW) and the combination of ketamine anesthesia (25 mg/kg BW) and xylazine (3 mg/kg BW). Second treatment (P2), the rabbits were injected with atropine (0,05 mg/kg BW) and the combination of ketamine anesthesia (25 mg/kg BW) and midazolam (2mg/kg BW). The measurements of intraocular pressure performed in minute 0, 15, 30, and 45 to each rabbit using tonometer Schiotz. The result showed that the Intraocular Pressure have no significant difference between the two treatments (p>0,05). However, it did showed significantly influences within the interval 0 to 45 minutes. The  conclusion that the ketamine-xylazine combination was safer than ketamine-midazolam combination for giving anesthesia to rabbits.

Keyword :

anesthesia, ketamine, xylazine, midazolam, intraocular pressure,


References :

Maulana,(2009) Profil Penggunaan Kombinasi Ketamin-Xylazin dan Ketamin-Midazolam sebagai AnestesiUmum Terhadap Lama Anestesi Umum Dan Gambaran Fisiologis Tubuh Pada Kelinci Surabaya : Skripsi

I Komang W Sardjana, Diah Kusumawati,(2004) Anestesi Veteriner Yogyakarta : Gadjah Mada University Press

Santosa, W,(2005) Pengaruh terhadap tekanan intraokuler perbandingan antara pretreatment rokuronium-suksinilkolin dengan rokuronium Semarang : Bagian Anestesiologi Fakultas Kedokteran Universitas Diponegoro Semarang

Tanjung H.,(2003) Perbedaan Rata-rata Pada Miopia dan Hipermetropia Di RSUPH Adam Malik Medan Medan : Fakultas Kedokteran Universitas Sumatra Utar





Archive Article

Cover Media Content

Volume : 1 / No. : 1 / Pub. : 2012-07
  1. The Correlation Between Breed And Obesity In Dogs In Surabaya
  2. Histopathology Of Renal Male Rats Of Femoral Fracture With Cissus Quadrangularis Plant Extract And Calcium Carbonate Therapy
  3. Treatment Of Canine Demodecosis In Veterinary Teaching Hospital Faculty Of Veterinary Medicine Airlangga University
  4. Combined Of Ampicilline, Dextran-40 And Dexamethason On The Prevention Of Intra-abdominal Adhesions Postoperative Hysterotomy In Cat (fellis Catus)
  5. Packed Cell Volume Comparison Of Dog Blood Before And After Storage Using Citrate-phosphate-dextrose
  6. Alkaline Phosphatase Blood Levels Before And After Rabbit Mandibula Bones Reconstruction By The Block Of Autograft Decortication And Non Decortication Technique
  7. The Profil Of Intraocular Pressure Using Combination Ketamine-xylazine And Ketamine-midazolam In Rabbit (oryctolagus Cuniculus)
  8. Case Study : Feline Polycystic Kidney Disease