UNIVERSITAS AIRLANGGA



Detail Article

Journal of Parasite Science

ISSN 2656-5331

Vol. 1 / No. 2 / Published : 2017-09

Order : 3, and page :47 - 50

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Original Article :

Anthelmintic activity of basil leaves (ocimum sanctum linn.) infusion against ascaris suum in vitro

Author :

  1. Ogen Sea*1
  2. Mas’ud Hariadi*2
  3. Setiawan Koesdarto*3
  4. Muchammad Yunus*4
  5. Kusnoto*5
  6. Ngakan Made R.W*6
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Dosen Fakultas Kedokteran Hewan
  4. Dosen Fakultas Kedokteran Hewan
  5. Dosen Fakultas Kedokteran Hewan
  6. Dosen Fakultas Kedokteran Hewan

Abstract :

      Ascaris suum is a parasite nematode that causes infection in swines with high prevalence rates in host populations and usually associated with liver damages called “milk spots” caused by larvae migration, resulting in organ condemnation. Basil leaves (Ocimum sanctum) phytochemical constituents contains flavonoid, phenol and tannin. Tannins and phenolics are known to interfere with the energy generation in helminth parasites by uncoupling oxidative phosphorylation and also bind to free proteins in the gastrointestinal tract of host animal or glycoprotein on the cuticle of the parasite and leading to death. This study was aimed to determine the activity of basil leaves (Ocimum sanctum) infusion in several concentrations against A. suum in vitro. This research used six treatments and four replications. This research used 10 A. suum in each treatment with four replication. The observations were done at 12, 18, 24, 30 and 36 hours in an incubator at 37oC. Based on the data analysis, basil leaves (Ocimum sanctum) infusion has anthelmintic activity against A. suum in vitro. The greater of the concentration and the longer of time of immersion, will make the death percentage of A. suum become higher. Concentration of basil leaves (Ocimum sanctum) infusion 15% is the effective concentration that can kill 100% of the A.suum during 36 hours of immersion.

Keyword :

basil leaves, infusion, Ascaris suum, in vitro,


References :

Andrew, R.W., C. Fryganas, A. Ramsay, Irene Mueller-Harvey, and M. T. Stig,(2014) Direct Anthelmintic Effects of Condensed Tannins from Diverse Plant Sources against Ascaris suum 9(5) : PLoS One

Bhatt,K.J,(2014) Ocimum sanctum: The Indian Medicinal plant 3(1):53-57 : Int. J. ChemTech.App.

Chandrasekaran, C.V., H.S. Srikanth, M.S.Anand,J.J. Allan,M.M. Viji and A. Amit,(2013) Evaluation of the Mutagenic Potential and Acute Oral Toxicity of Standardized Extract of Ocimum sanctum (OciBest(TM)). Human and Exp 32: 992-1004 : Toxicol





Archive Article

Cover Media Content

Volume : 1 / No. : 2 / Pub. : 2017-09
  1. Prevalence Of Trypanosomiasis Of Wild Rats (rattus Sp.) In Banyuwangi
  2. Effect Of Garlic (allium Sativum) Infusion On The Time Of Death Of Ascaridia Galli
  3. Anthelmintic Activity Of Basil Leaves (ocimum Sanctum Linn.) Infusion Against Ascaris Suum In Vitro
  4. Infestation Pattern Of Lice In Laying Ducks In Village Of Kramat District Of Bangkalan Region Of Bangkalan
  5. The Anthelmintic Activity Of Ethanol Extract Of Basil Leaves (ocimum Americanum Linn.) Againt Haemonchus Contortus Death In Vitro
  6. Anthelmintic Potential Extract Mango Gadung Seed (mangifera Indica L.) Mecistocirrus Digitatus In Vitro

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