Majalah Ilmu Faal Indonesia
ISSN 0215-1995
Vol. 8 / No. 1 / Published : 2008-10
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Original Article :
Pengaruh pemberian ekstrak daun jambu biji terhadap kadar malondialdehide otot extensor digitorum longus rattus norvegicus akibat olahraga anaerobik
Author :
- Yayuk Susilawati*1
- Departemen Biokimia Fakultas Kedokteran Universitas Airlangga
Jl. Prof. Dr. Moestopo No. 47 Surabaya
Abstract :
The aim of this study was to find the effect of Psidium guajava l. leaves extract on Extensor digitorum longus muscle MDA level in Rattus norvegicus resulting from anaerobic exercise. The study was a laboratory experimental study using the randomized post test only control group design. There were three groups in this study (groups 1, 2 and 3). Group 1 was control, receiving only anaerobic exercise, without the extract. Group 2 and 3 received anaerobic exercise and the extract of Psidium guajava l. leaves in different doses. The doses are for group 2 dose 5.407 mg/200 g BW rats and group 3 dose 10.813 mg/200 g BW rats. The extract was given 3 hours before anaerobic exercise. Each subject in those groups was followed-up for 6 days. The groups were subjected to Extensor digitorum longus muscle MDA level examination on the last day (day 6). The results of this study revealed that Extensor digitorum longus muscle MDA level in control group showed significant reduction (p = 0.012 and p = 0.016 or p < 0.05) in groups P1 and P2 (P1 = 0,067 ± 0,007 and P2 = 0,070 ± 0,010) compared to control group (C = 0,123 ± 0,050). These data suggest that the administration of Psidium guajava l. leaves extract for 6 days provide inhibitory effect against the increase of Extensor digitorum longus muscle MDA level resulting from anaerobic exercise.
Keyword :
Psidium guajava l. leaves, anaerobic exercise, Malondialdehyde (MDA),
References :
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