Majalah Ilmu Faal Indonesia
ISSN 0215-1995
Vol. 5 / No. 2 / Published : 2006-02
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Original Article :
Plasticity biologis sel imunokompeten pada pemberian dexamethason
Author :
- Sunarko Setyawan*1
Abstract :
Immune system show ”up and down regulation ” or plasticity phenomen. Immunomodulator of glucocorticoid for immunocompeten cells plasticity are not clear. Times series experimental study used 32 Rattus norvegicus strain Wistar that 12 weeks years old, 225-250 gram body weight. Administration of dexamethason is 0,05 mg via intraperitoenal injection everyday. Sample divided to 4 groups; (1) no administration of dexamethason, (2) 3 days of dexamethason administration, (3) 6 days of dexamethason administration and (4) 7 days recovery after 6 days of dexamethason administration. Measurement of neutrophil and lymphocyte used intracardial blood aspiration (ether anesthetic) with peroxidase technique of Technicon-1. The result of each groups are; (1) neutrophil (3,42 ± 0,84 ; 6,07 ± 1,45; 4,30 ± 1,32; 2,29 ± 1,06 x10.e3/uL, p
Keyword :
Immunocompetence cells, Dexamethason, Plasticity,
References :
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