UNIVERSITAS AIRLANGGA



Detail Article

Majalah Obstetri & Ginekologi

ISSN 0854-0381

Vol. 21 / No. 2 / Published : 2013-05

Order : 7, and page :84 - 88

Related with : Scholar   Yahoo!   Bing

Original Article :

Comparison of anti-mullerian hormone (amh), basal follicle stimulating hormone (fsh), estradiol and antral follicles count as predictors of ovarian response in in vitro fertilization program

Author :

  1. Samsulhadi*1
  2. Relly Y Primariawan*2
  3. Kadek Dharma Widhiarta*3
  1. Dosen Fakultas Kedokteran
  2. Dosen Fakultas Kedokteran
  3. Mahasiswa Fakultas Kedokteran

Abstract :

Ovarian stimulation response is crucial to be identified in in vitro fertilization program. There are several markers to identify suchresponse, including AMH, basal FSH, estradiol and AFC. This study aimed to find the difference AMH, basal FSH, estradiol andAFC as ovarian responsepredictors. This was an observational analytic study in infertile patients. Subjects performed bloodsampling 3-day menstrual cycle for inspection of AMH, basal FSH, E2 basal and antral follicle number calculation (AFC). Based onoocytes the number, the subjects were divided into groups of poor responders ( 4 oocytes) and good responders (oocytes 5-15). Weperformed correlation and regression test between AMH, basal FSH, AFC, and basal E2 with three indicators of ovarian stimulationresponse (number of oocytes at OPU, the number of preovulatory follicles and E2 levels at hCG administration).The results showeda significant difference in AMH levels (p = 0.001), basal FSH (p = 0.045), and AFC (p = 0.001) between poor and good responders.AMH correlated strongly and significantly with OPU (r = 0843, p = 0.001), number of preovulatory follicles (r = 0577, p = 0.001),and current E2 administration HCG (r = 0701 and p = 0.001). AFC also show a strong and significant correlation with the OPU (r= 0721, p = 0.001), number of preovulatory follicles (r = 0555, p = 0.002), and current E2 administration HCG (r = 0435, p =0021). Only basal FSH obtained by OPU had significant correlation (r = -0420, p = 0026). Basal E2 showed no significantcorrelations on all three indicators of ovarian response. In conclusion, AMH is a better predictor of ovarian response than AFC,basal FSH and basalE2.(MOG 2013;21:84-88)

Keyword :

AMH, basal FSH, basal E2, AFC, ovarian response,


References :

Leridon H,(2007) Studies of fertility and fecundity: comparative approaches from demography and epidemiology - : C. R. Biologies

Broekmans FJ, Soules MR and Fauser BC,(2009) Ovarian aging: mechanisms and clinical consequences - : Endocr





Archive Article

Cover Media Content

Volume : 21 / No. : 2 / Pub. : 2013-05
  1. Radiotherapy Response Of Advanced Squamous And Adenocarcinoma Types Of Cervical Cancer At Dr Soetomo Hospital Surabaya
  2. Radiotherapy Outcome In Stage Iib Cervical Cancer Patients Resistant To Neoadjuvant Chemotherapy At Dr. Soetomo Hospital 2006 – 2010
  3. Correlation Between Risk Factors And Pelvic Organ Prolapse In Gynecology Outpatient Clinic, Dr. Soetomo Hospital Surabaya, 2007 – 2011
  4. Visualization Of Endometrial And Uterine Cavity Structure Abnormality With Transvaginal Sonography, Color Doppler Transvaginal Sonography And Saline Infusion Sonography In Abnormal Uterine Bleeding
  5. Expressions Of Growth Differentiation Factor-9 (gdf-9) Of Bovine Cumulus-oocyte Complex In Peritoneal Fluid Culture Of Infertile Patients With Endometriosis
  6. Viral Load Pada Kanker Serviks Terinfeksi Human Papilloma Virus Tipe 16
  7. Comparison Of Anti-mullerian Hormone (amh), Basal Follicle Stimulating Hormone (fsh), Estradiol And Antral Follicles Count As Predictors Of Ovarian Response In In Vitro Fertilization Program

Information index.php/JIPK/tmp_tumb/MOG