UNIVERSITAS AIRLANGGA



Detail Article

Majalah Obstetri & Ginekologi

ISSN 0854-0381

Vol. 17 / No. 1 / Published : 2001-01

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Original Article :

Correlation of basal serum amh level with ovarian response to ovulatory stimulation in in vitro fertilization program

Author :

  1. Putu Doster Mahayasa*1
  2. Samsulhadi*2
  3. Aucky Hinting*3
  1. -
  2. -
  3. -

Abstract :

Anti-Mullerian Hormone (AMH), produced by pre-antral and antral follicular granulosa cells, has a role in limiting primordial follicular number to develop into primary follicles. Its level can be measured in the serum, which is relatively not fluctuating along the menstrual cycle and its level is decreasing gradually along with the increasing age of a woman. The number of developing follicles depends on the number of remaining follicles in the ovary and the numbers of mature follicles. The number of oocytes obtained in ovarian stimulation depends on the developing follicular number. Therefore, the examination of serum basal AMH level can indirectly describe ovarian reserve and predict ovarian response on ovulatory stimulation. The objective of this study was to examine correlation of basal serum AMH level and ovarian response with ovulatory stimulation in in vitro fertilization program. Population was women who met the inclusion criteria to participate the in vitro fertilization program in Fertility Clinic, Siloam Hospital, Surabaya, and Graha Amerta, Surabaya, from Februari 2007. Samples comprised 69 persons. AMH level was examined on day 3 menstruation along with the examination of other basal hormones. Data were collected during stimulation process up to ovarian harvesting procedure, which included total gonadothropin ampules, serum E2 level during hCG, pre-ovulatory folicular count, and oocyte count. Statistical analysis was undertaken using Pearson’s correlation test to identify intervariable correlation. The result of this study revealed significant correlation between basal serum AMH level and pre-ovulatory follicular count (r = 0.529, p < 0,01), oocyte count (r = 0.535, p < 0.01), serum E2 level during hCG administration (r = 0.456, p < 0.01), and total gonadothropin ampules per pre-ovulatory follicle (r = -0.311, p < 0.01).

Keyword :

basal serum AMH level, ovarian response, ovulatory stimulation,


References :

Te Velde ER, Pearson PL,(0000) The variability of female reproductive ageing :





Archive Article

Cover Media Content

Volume : 17 / No. : 1 / Pub. : 2009-01
  1. Effect Of Curcumin On Vegf Expression And Size Of Endometriotic Implant (experimental Study On Endometriotic Mice Model)
  2. Effect Of Different Duration Administration Of Testosterone On Insulin Resistance Index And Free Fatty Acid Concentration. An Experimental Study On Pcos In Rats.
  3. Correlation Of Basal Serum Amh Level With Ovarian Response To Ovulatory Stimulation In In Vitro Fertilization Program
  4. Expression Of αvβ3 Endometrium After Clomiphene Citrate, N-acetyl L-cystein, Or Combination Of Clomiphene Citrate And N-acetyl L-cystein Given To Polycystic Ovarian Syndrome Case
  5. Pregnancy With Generalized Pustular Psoriasis

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