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Detail Article

Majalah Obstetri & Ginekologi

ISSN 0854-0381

Vol. 19 / No. 2 / Published : 2011-05

Order : 4, and page :73 - 77

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Original Article :

Increased expression of myocyte hsp27 and myometrium contraction on new zealand rabbit following surabaya method uterine compression suture after cesarean delivery

Author :

  1. Widjiati*1
  2. Iik Sumarni*2
  3. Agus Sulistyono*3
  1. Dosen Fakultas Kedokteran Hewan
  2. Mahasiswa Fakultas Kedokteran
  3. Dosen Fakultas Kedokteran

Abstract :

Surabaya uterine compression suture is a modification from BLynch procedure as one of compression technique for management hemorrhage due to uterine atony. This study looks at on the number of HSP 27 expression on myosit, number of contracted myocyte and number of compressed radial uterine artery on New Zealand rabbit uterus at half hours and two hours after Surabaya compression. Twenty adult female New Zealand rabbit is induced for pregnancy. All are given birth by cesarian section. Population divided as two groups from each rabbit one uteri side as exposure group which undergone uterine compression suture using surabaya method and the other side as control group with no exposure to uterine compression suture. Histopathology specimen is taken from study and control group and count on the number of expression HSP 27, total contracted myocyte and total compressed radial uterine artery which after observed at half hour and two hours. Statistic analysis using couple T test shows increase on HSP 27 expression, total contracted myocyte, total compressed radial uterine artery at study group compare to control group (p<0.001) on half hour observation. However on two hours observation, there is still significant differ on HSP 27 expression between two groups but no differs on total contracted myocyte and compressed artery. In conclusion, mechanic stimuli using Surabaya uterus compression increases HSP 27 expression, total contracted myosit cells and thinning artery after 30 minutes and remained the same for HSP 27 expression after two hours. (MOG 2011;19:73-77)

Keyword :

Surabaya method compression suture, HSP 27 expression, contracted myocyte, hemorrhagic post partum, -,


References :

Anderson JM and Etches D,(2007) Prevention and management of postpartum hemorrhage - : American academy of family physicians

Al-Zirqi I, Vangen S, Forsen L and Pedersen,(2008) S. Prevalence and risk factors of severe obstetric haemorrhage - : BJOG





Archive Article

Cover Media Content

Volume : 19 / No. : 2 / Pub. : 2011-05
  1. Perbandingan Ekspresi P16ink4a Antara Pap Smear Low Grade Squamous Intraepithelial Lesion Dengan High Grade Squamous Intraepithelial Lesion
  2. Comparison Between Early-onset And Late-onset Preeclampsia By Echocardiographic Examination Of Cardiac Output, Total Vascular Peripheral Resistance, And Doppler Velocimetry Examination Of Uterine Artery Resistance Index
  3. Comparison Of Pap Smear Examinations Result Between Post Leep And Electrocauter In Low-grade Squamous Intraepithelial Lesion Patients
  4. Increased Expression Of Myocyte Hsp27 And Myometrium Contraction On New Zealand Rabbit Following Surabaya Method Uterine Compression Suture After Cesarean Delivery
  5. Intraamniotic Infection Diagnostic Test In Pprom Through The Measurement Of Vaginal Fluid C-reactive Protein Using Hs-crp Check-1 (lateral-flow Immunoassay Method) With Cobas Integra 400 Plus (light-scattering Immunoassay Method) As A Gold Standard
  6. Perbandingan Antara He4,ca-125, Dan Kombinasi He4 & Ca-125 Sebagai Tumor Marker Pada Pasien Kanker Ovarium Tipe Epitel
  7. Profil Kadar Kit-ligand Pada Zalir Folikel Ovarium Pada Pasien Infertil Dengan Endometriosis Ringan, Berat Dan Tanpa Endometriosis

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