UNIVERSITAS AIRLANGGA



Detail Article

OVOZOA

ISSN 2302-6464

Vol. 6 / No. 2 / Published : 2017-10

Order : 10, and page :132 - 137

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Original Article :

Pengaruh insuline like growth factor-i (igf-i) serum kuda bunting crossbreed dibandingkan dengan insuline-like growth factor-i (igf–i) recombinant terhadap jumlah anak mencit (mus musculus)

Author :

  1. M. Nahil Fahsya*1
  2. Dr. Tjuk Imam Restiadi, drh., M.Si.*2
  3. Hasutji Endah Narumi, drh., M.P.*3
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Dosen Fakultas Kedokteran Hewan

Abstract :

This study was conducted to prove the effect of Insulin-Like Growth Factor-I (IGF-I) derived from pregnant crossbreed mare serum (PMS) compared to IGF-I recombinant mouse on litter size in mice (Mus musculus). The subject of this research were 35 female mice and 21 male mice. The research was arranged by Completely Randomized Design (CRD) with seven treatment and five replications. The treatment were K0 = 0.1 ml of physiological NaCl, P1 = 10 ng/ml of IGF-I PMS, P2 = 20 ng/ml of IGF-I PMS, P3 = 40 ng/ml of IGF-I PMS, P4 = 10 ng/ml of IGF-I recombinant mouse, P5 = 20 ng/ml of IGF-I recombinant mouse, and P6 = 40 ng/ml of IGF-I recombinant mouse. Observed variables include litter size in mice. The data were analyzed by Analysis of Variance (ANOVA), followed by HSD (Honestly Significant Difference), by SPSS 21 for Windows program with a significance level of p<0,05. The result effect of Insulin-Like Growth Factor-I (IGF-I) derived from pregnant crossbreed mare serum (PMS) and IGF-I recombinant mouse on litter size in mice (Mus musculus)  did not significantly difference (p>0,05). Different test results indicate that there are significant differences between the addition 0.1 ml of physiological NaCl with 40 ng/ml of IGF-I PMS.

Keyword :

IGF-I, IGF-I pregnant crossbreed mare serum, litter size, Mus musculus,


References :

Block, J., C. Wrenzycki, H. Niemann, D. Herrmann and P.J. Hansen. ,(2008) Effects of insulin-like growth factor- 1 on cellular and molecular characteristics of bovine blastocyst produced in vitro. 75: 895-903 : Mol. Reprod. Dev.

Cushman, R.A., V.S. Hedgpeth, S.E. Echternjkamp and J.H. Britt. ,(2000) Evaluation of numbers of microscopic and macroscopic follicles in cattle selected for twinning. 78: 1564-1567. : J. Anim. Sci.

Jousan, F.D. and P.J. Hansen. ,(2007) Insulin-like growth factor-I promotes resistance of bovine preimplantat ion embryos to heat shock through actions independent of its anti-apoptotic actions requiring PI3K signaling. 74: 189-196. : Mol Reprod. Dev.

Lackey, BR., S.L.L. Gray., and D.M. Henricks. ,(2000) Physiological Basis for Use of Insuline-Like Growth Factor in Reproductive Applications: A Review. 53: 1147-1156. : Theriogenology

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Archive Article

Cover Media Content

Volume : 6 / No. : 2 / Pub. : 2017-10
  1. Sex Ratio Fetus Jantan Dan Betina Pada Mencit ( Mus Musculus ) Setelah Injeksi Dengan Hy-antisera Pada Induk Mencit ( Mus Musculus ) Secara Intravena
  2. Efisiensi Reproduksi Dan Status Fertilitas Sapi Peranakan Ongole (po) Akseptor Ib Di Dataran Tinggi Dan Dataran Rendah Kabupaten Blora
  3. Pengaruh Vitamin C Dan Vitamin E Sebagai Tindakan Preventif Terhadap Jumlah Sel Spermatogenik Testis Mencit (mus Musculus) Yang Dipapar Boraks
  4. Deteksi Brucellosis Pada Susu Sapi Perah Di Peternakan Desa Tropodo Kecamatan Krian Kabupaten Sidoarjo Dengan Metode Pemeriksaan Polymerase Chain Reaction (pcr)
  5. Pengaruh Suhu Terhadap Viabilitas Spermatozoa Dalam Lendir Serviks Sapi Perah Estrus Secara In Vitro
  6. Pengaruh Ekstrak Daun Lampes (ocimum Sanctum Linn) Terhadap Motilitas Dan Viabilitas Spermatozoa Mencit (mus Musculus)
  7. Pengaruh Waktu Gliserolisasi Berbeda Terhadap Viabilitas Dan Motilitas Spermatozoa Sapi Bali (bos Sondaicus) Dalam Pengencer Tris Kuning Telur
  8. Profil Progesteron Pada Sapi Perah Yang Diinduksi Luteinizing Hormone (lh) Setelah Inseminasi
  9. Kejadian Kawin Berulang Pada Sapi Potong Di Kecamatan Wonomerto Kabupaten Probolinggo Jawa Timur
  10. Pengaruh Insuline Like Growth Factor-i (igf-i) Serum Kuda Bunting Crossbreed Dibandingkan Dengan Insuline-like Growth Factor-i (igf–i) Recombinant Terhadap Jumlah Anak Mencit (mus Musculus)
  11. Determinasi Faktor-faktor Penyebab Milk Fever Pada Sapi Perah Di Koperasi Peternakan Sapi Perah (kpsp) Setia Kawan Kecamatan Tutur Pasuruan
  12. Efisiensi Reproduksi Sapi Perah Akseptor Ib Di Wilayah Kerja Kpsp Setia Kawan, Nongkojajar, Pasuruan
  13. Pengaruh Perbedaan Waktu Sentrifugasi Dengan Metode Swim Up Spermatozoa Terhadap Keutuhan Membran Dan Nekrosis Spermatozoa Domba Sapudi
  14. Tingkat Keberhasilan Program Gertak Birahi Dan Inseminasi Buatan (gbib) Pada Kerbau Toraya Di Dinas Peternakan Kabupaten Toraja Utara Tahun 2015
  15. Identifikasi Trypanosoma Sp Pada Tikus Liar (rattus Sp) Di Kecamatan Bangkalan, Kabupaten Bangkalan, Madura Dengan Metode Polymerase Chain Reaction (pcr)

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