UNIVERSITAS AIRLANGGA



Detail Article

OVOZOA

ISSN 2302-6464

Vol. 2 / No. 2 / Published : 2013-10

Order : 11, and page :82 - 90

Related with : Scholar   Yahoo!   Bing

Original Article :

The effect of bitter melon fruit (momordica charantia l.) extract on pregnancy rate and litter size of mice (mus musculus)

Author :

  1. Rr. Sri Pantja Madyawati*1
  2. Mia Zakia Romadhoni*2
  3. Sri Mumpuni Sosiawati*3
  1. Departemen Reproduksi Veteriner Fakultas Kedokteran Hewan, Universitas Airlangga
  2. Mahasiswa Fakultas Kedokteran Hewan Unair
  3. Departemen Parasitologi Fakultas Kedokteran Hewan Unair

Abstract :

The aim of this study was to find out of the effect of bitter melon fruit (Momordica charantia L.) extract on pregnancy rate and litter size of mice  (Mus musculus) . It  based on active content  from bitter melon fruit that is triterpenoid and flavonoid which influencing the ovary follicle  development. Those active content work through inhibition of mechanism GnRH secretion then follicle undeveloped. This study using 6 times RAL. The study used bitter melon fruit exstract dosage 0 mg/kg bw, 667 mg/ kg bw, 1000 mg/kg bw and 1333 mg/kg bw then diluted with CMC 0,5% administered 2 times a day during 10 days 0,5 ml per oral. The animal used is 24 fertile female mice. After  treatment the mice collected with male during 5 days then separated and make an observation. The result data from the study  included pregnancy rate and litter size of mice. The study indicating that there is an effect of bitter melon fruit extract on pregnancy rate and litter size of mice. The real effect (P ≤ 0,05) indicated in dose 1000 mg/kg bw and decrease in dose 1333 mg/kg bw with pregnancy rate reduction consecutively 33% and 100%.

Keyword :

Momordica charantia L., pregnancy rate, litter size,


References :

Ifeanyi, A.C., Y.O. Eboetse., D.F. Ikechukwu., O.A. Adewale., N.C. Carmel and O.A. Olugbenga. ,(2011) Effect of Momordica charantia on Estrous cycle of Sparague-Dawley Rats. USA : Pacific Journal of Medical Sciences. 8(1): 37-48.

Hafez, E.S.E and B. Hafez. ,(2000) Reproduction Farm Animals. Seventh Edition. Lippincott Williams and Wilkins. USA : Kiawah Island. 24-26: 13-17.





Archive Article

Cover Media Content

Volume : 2 / No. : 2 / Pub. : 2013-10
  1. Extract Of Annona Muricata As Egg Yolk Citrate Diluent Substitute For Fat-tailed Sheep Sperm Quality
  2. Effect Of Different Injection Time Of Pregnant Mare Serum Gonadotropin (pmsg) On The Onset Of Estrous Of Fat Tailed Ewes Synchronized Using Intravaginal Progesterone
  3. The Effect Of A Diluent Contained Lecithin On The Quality Post Thawing Carp’s (cyprinus Carpio) Spermatozoa
  4. Effect Of Glycerol In Skim Egg Yolk Diluent On The Freezing Of Goldfish Spermatozoa (cyprinus Carpio)
  5. The Effect Of Clove Tea ( Syzygium Aromaticum ) On Histopathological View Of Mouse (mus Musculus) Testis With Cigarette Smoke Exposured
  6. Extract Banana An As Alternative Fructose Toward A Quality Of Fat-tailed Shepp’s Sperm
  7. Fertilization Rate Of Merino Sheep Frozen Semen In Diluent Egg Yolk Tris And Egg Yolk Skim To In Vitro Fertilization
  8. Reproductive Efficiency Of Beef Cattle Resulted From Artificial Insemination In Wringin Subdistrict, Bondowoso District In 2012
  9. Artificial Insemination Program For Beef Cattle In Madura Island “targets, Realisation And Problems”
  10. Effect Of Infusum Salam Leaves (eugenia Polyantha) Testis Spermatogenic Cells Amount Of White Rats (rattus Norvegicus) Induced Alloxan
  11. The Effect Of Bitter Melon Fruit (momordica Charantia L.) Extract On Pregnancy Rate And Litter Size Of Mice (mus Musculus)
  12. The Effect Of Giving Protein Fertility Associated Antigen (faa) To Capacitation And Acrosome Reaction On Frozen Semen Simental Bull After Centrifugation
  13. Effect Of Seminal Plasm Of Cow On Goat’s Spermatozoa Motility And Viabilityin In Milk Diluter
  14. The Effect Of Caffeine In Washing And Capacitation Media Of The Goat Spermatozoa On Pregnancy Rates Of Local Goat

Information index.php/JIPK/tmp_tumb/OVOZOA