UNIVERSITAS AIRLANGGA



Detail Article

Jurnal Rekonstruksi & Estetik

ISSN 2301-7937

Vol. 2 / No. 1 / Published : 2013-01

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Original Article :

The effect of amnion freeze – drying to prevent adhesion in rabbit tendon achilles healing

Author :

  1. Franky Prilyanda*1
  2. M. Sjaifuddin Noer*2
  1. mahasiswa
  2. dosen

Abstract :

Background: The main aim of tendon surgery is to restore preserves tendon gliding. The formation of peritendinous adhesion around the repair site is one of several adverse event that may prevent achievement of this aim. The freeze - drying amniotic derives from the fetal membranes which consist of two layers that may have a function as a barrier in the formation of peritendinous adhesion, rich of collagent, accelerate the epitelization and preventing fibrotic tissue formation. Those content of the amniotic membrane could prevent the formation of peritendinous adhesion in tendon healing. The objective of this study was to investigate the use of freeze - drying amniotic membrane as a long-term bioprosthesis in hand surgery. The role of freeze – drying amniotic membrane was investigated in rabbit with regard to the prevention of adhesion formation following Achilles tendon repair. Material and Method : The experimental research  use 32 New Zealand rabbits, devided into two groups. On all group, one of the Achilles tendon was sharply devided, group I was treated by Freeze-drying amniotic, and group II was not treated Freeze-drying amniotic (control). After ten days, the animal were killed, and phatology anatomy examination was done on therepair site. The adhesion was assessed under light microscope with see the number of fibroblast Result : Histologic examination demonstrated that use of the freeze – drying amniotic membrane significantly reduced the amount of adhesion compared with the other groups . 10 day after implantation no remnants of freeze – drying amniotic membrane could be identified at the tendon repair site. Conclusion : Freeze–drying amniotic membrane is easily prepared, and because of its cost effectiveness, its use in the prevention and treatment of adhesions should always be kept in mind.

Keyword :

Freeze–drying Amniotic membrane, repair, reconstruction, adhesion,


References :

Stricland JW,(1999) Flexor tendon-acute injury. In : Green DP, Hotchkiss RN, Pederson WC, editor Philadelphia : Churchill Livingstone

Sharma P., Maffulli N,(2005) Tendon Injury and Tendynopathy: Healing and Repair New York : J Bone Joint Surg Am

Rockwood C A., Green D P,(1996) Healing of the Musculoskeletal Tissues. in Fracture in Adults Philadelphia : Lippincott-Raven





Archive Article

Cover Media Content

Volume : 2 / No. : 1 / Pub. : 2013-01
  1. The Effect Of Intravenous Vitamin C On Nitric Oxide Serum Level In Severe Burn Injury
  2. Effectivity Of Topical Chitosan On Exudative Chronic Wound Management
  3. Bactericidal Effect Of Topical Vitis Vinifera On Methicillin-resistant Staphylococcus Aureus (mrsa) On Rattus Norvegicus Skin Wound
  4. Pengaruh Pemberian Topikal Low Molecular Weight Hyaluronate Pada Epitelialisasi Luka Superfisial Tikus Putih Yang Dirawat Dengan Membran Amnion Freeze-dried
  5. The Effect Of 3000 Mg Vitamin C Infusion On Histamine Level In Severely Burned Patients
  6. The Effect Of Amnion Freeze – Drying To Prevent Adhesion In Rabbit Tendon Achilles Healing
  7. Five Years Retrospective Study Of Burns In Dr. Soetomo General Hospital Surabaya
  8. Analyzing Post-reconstruction Facial Anthropometric, Cephalometric Parameters And Proportion Of Facial Edema On Maxillofacial Trauma Patients
  9. The Nasal Profile Of Young Indonesian Women Aged 19-21 Years Old Judged To Be Atractive According To Third Year Medical Students Of Airlangga University
  10. Eye Profile Of Indonesian Young Women Aged 19-21 Years Judged To Be Attractive By Third Year Medical Students Of Airlangga University

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