ISSN 1979-1305
Vol. 3 / No. 1 / Published : 2010-02
Order : 14, and page :65 - 68
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Original Article :
Benzopyrene induce apoptosis of the lung cells in ratus norvegicus
Author :
- Muhamad Agus Wibowo*1
- Sofwan Anwari*2
- Aulanni'am*3
- Fakultas MIPA, Universitas Tanjungpura
- Fakultas Kehutanan, Universitas Tanjungpura
- Fakultas MIPA, Universitas Brawijaya
Abstract :
Apoptosis is importen in physiologic and pathologic processes such as tumor regression, embryogenesis, andnormal cell turnover. ROS is molecule that importen to induce DNA damage and apoptosis of cell. Increasing of ROSexpression can be induce by carcinogenic compounds as benzopyrene. This research have been tested of inducingapoptosis by benzopyren that mediated by ROS. The data of research indicating that benzopyrene can increasingapoptosis of lung cells and increasing of ROS. Base on the data of this research, we understood that benzopyrene caninduce apoptosis of lung cells by ROS path ways.
Keyword :
Benzopyrene, Apoptosis, ROS, ., .,
References :
Los, M. & H. Walczak,(2002) Caspases- The Role in Cell Death and Cell Survival New York : Kluwe Academic/ Plenum Publishers
Magesh, V., R. Venugopal, K.D. Bhavani, & D. Sakthisekaran,(2007) Effect of Crocetin on Benzo(a) Pyrene Induced Lung Carcinogenesis in Swiss Albino Mice . : Int. J. Cancer Res.
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Volume : 3 / No. : 1 / Pub. : 2010-02 |
- Apllication Of Frozen Semen Plus Tyrosine Kinase To Increased Conception Rate Of Beef Cattle
- Isolation, Identification And Characterization Of Inhibin B Protein Of Rattus Norvegicus Sertoli Cell Culture As Male Hormonal Contraception Candidate
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- The Potency Of A Black Soybean Milk And Yellow Soybean Milk On The Level Of Triglycerides In Rat (rattus Novergicus) Fed With A High Fat Diet
- The Effect Of Centrifugation On Quality Of Motility, Viability And Acrosom Cap Of Goat Sperm
- Benzopyrene Induce Apoptosis Of The Lung Cells In Ratus Norvegicus
- Partenogenetik Development Of Mouse Oocytes Activation Using Ethanol And 6-dmap By In Vitro
- Identification Of Pregnancy Specific Protein B (pspb) From Placenta Foetalis (cotyledon) Freishian Holstein Cows
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