UNIVERSITAS AIRLANGGA



Detail Article

Veterinaria Medika

ISSN 1979-1305

Vol. 6 / No. 3 / Published : 2013-11

Order : 7, and page :189 - 172

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Original Article :

Ethanol extract of noni fruit activity (morindacitrifolia l.) against expressions of ifn- γ at balb/c mice spleen which infected by salmonella typhimurium

Author :

  1. Rahardjo, S.S*1
  2. Suwanti, L.T*2
  3. Meles, I.D.K*3
  1. Pascasarjana Vaksinologi dan Immunoterapetika Fakultas Kedokteran Hewan Unair
  2. Fakultas Kedokteran Hewan Universitas Airlangga
  3. Fakultas Kedokteran Hewan Universitas Airlangga

Abstract :

Salmonellosis was caused by a Salmonella spp. bacteria and have ability to attack both of animaland human or zoonosis. S. typhimurium  cause calf illness with increasing mortality and enteritis at United States and some countries in Europe, and Enteritic as pathognomonical sign could caused mortality with dehydration and intestinal lesion. Ethanol extract of noni fruit was able  stimulated cytokines product frommurine effector cell  such as Interleukin (IL) 1, IL-12, and IFN- γ.The IFN-γ from Th1 cell at post infectedwith Salmonellathypimurium condition, absolutely the major factor to activated macrophage and increasing killing activity and make cell which infected Salmonella thypimurium, getting lysis. The purpose of this research,observe and count lymphocytes which IFN-γ expression at spleenwith IHC after give Salmonella thypimurium infectoin. Results has shown lymphocytes which IFN-γ expression have given a significant difference(P<0.05) among group. The conclusion of this research was Ethanol extract of noni fruit able to increasingIFN-γ expression onBALB/C mice spleen.

Keyword :

Salmonella typhimurium, Ethanol extract of noni fruit, IFN-γ,


References :

Broz P, Maikke B.C and Denise M.M.,(2012) Innate Immune Respon to Salmonella typhimurium a Model Enteric Pathogen. . : Gut Microbes. 3:2, 62 – 70.

Coburn, B., Grassl, G.A., and Finlay, B.B.,(2007) Salmonella, the host and disease: a brief review. . : Immunol. Cell Biol. 85, 112–118.





Archive Article

Cover Media Content

Volume : 6 / No. : 3 / Pub. : 2013-11
  1. Effects Of Curcuma Zedoariarosc.administration To Dawley Mice Prior And After Dmba Initiation On The Expression Of Cyp1a1 Enzyme
  2. Effectiveness Of Crioprotectant During Sperm Freezing Process Using Rapid Freezing Method Toward The Concentration Of Post Thawing-frozen Cow Semen Dna
  3. The Effectiveness Of Garlic (allium Sativum L.) Extract In Chicken Broiler’s Titer Antibodies That Vaccinated With Live Nd
  4. Reactivity Ib (infectious Bronchitis) Virus Field Isolate Passaged On Embryonated Chicken 1 Eggs Against Antibody Post Vaccination
  5. Different Animals Species Hairs As Biological Tool For The Veterinary Forensic Assessement Of Three Types Of Dogs, American Pitbull Terrier, German Shepherd And Doberman
  6. Effect Of Cdp-choline To Reduce The Amount Of Necrosis Fibrouse Astrocyte In Cerebral Medula Of White Rats (rattus Novergicus) Exposed By Methylmercury
  7. Ethanol Extract Of Noni Fruit Activity (morindacitrifolia L.) Against Expressions Of Ifn- γ At Balb/c Mice Spleen Which Infected By Salmonella Typhimurium
  8. Study On Protein Expression Of Post-vaccination And Bird Flu H5n1 Virus Infection In Chickens
  9. Detection Diclazuril-resistant Eimeria Tenella At One Of Local Poultry In Kediri
  10. Combination Effect Of Echinacea Purpurea And Andrographis Paniculata As Hepatoprotector In White Rat Exposed By Heat Stress-
  11. The Featuring Liver Histpathology Of Aeromonas Hydrophila Infected Common Gouramy (osphronemus Gouramy Lac.) That Treated Meniran (phyllanthus Niruri Linn.) Leaf Infusum
  12. Taking Casein From Expired Skim Milk
  13. Potential Of Concentrate Feed And Lactation Periods On Milk Production And Lactosa Dairy Cattle Friesian Holstein Crossbred
  14. The Effect Of Tea Leaves (camellia Sinensis) Boiled, Guava Leaves (psidium Guajava Linn) Boiled, And Acacia Skin (acacia Mangium Willd) Boiled To Physical Quality Of Chicken Eggs
  15. Early Detection Of Brucellosis Reactor On Dairy Cattle In Kerjen Village, Srengat Sub District, Blitar District By Rose Bengal Test

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