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Detail Article

Veterinaria Medika

ISSN 1979-1305

Vol. 7 / No. 1 / Published : 2014-02

Order : 5, and page :31 - 36

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Original Article :

The effect of exposing pregnant rat (rattus novergicus) to particulate matter on congenital disorder and resorption of embryos

Author :

  1. Widjiati*1
  2. Eka Pramyrtha Hestianah*2
  3. Viski Fitri Hendrawan*3
  4. Epy Muhammad Luqman*4
  5. Rudi Sukamto*5
  1. Dosen Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Program Studi kedokteran Hewan Universitas Brawijaya
  4. Dosen Fakultas Kedokteran Hewan
  5. Dosen Fakultas Kedokteran Hewan

Abstract :

This research is a teratogenic research model intended to observe the effects caused by exposure to particulate matter (PM) which is one of the components of air pollutants which are cytotoxic.This research aims to study the effect of exposure length and dosage of particulate matter on congenital disorder and embryonic resorption . Particulate matter dosage used in this research was 532 mg / m³ and 1064 mg / m³ under the exposure of 4 hours and 8 hours. The observation was made on congenital disorder and the number of embryonic resorption during pregnancy. The results showed that there was a decrease in fetal weight and fetal body length. The fetal weight of KO was (2.18 ± 0.21) , K1 (1.53 ± 0.11) , K2 (1.45 ± 0.98) , K3 (1.26 ± 0.11) and K4 (0 , 39 ± 0.11) . The fetal body length of K0 group was (0.72 ± 0.44) , K1 (0.73 ± 0.75) , K2 (0.23 ± 0.02) , K3 (0.13 ± 0.03) and K4 (0.43 ± 0.00) . on the other hand, there was an increase in the percentage of embryonic resorption in the rats of the treatment groups when compared to the control group K0 (0.0 %) respectively K1 (4.3 %) , K2 (9.5 %) , K3 (22.7 %) and K4 (43.3 %). The conclusion is that the increased dosage and length of exposure to particulate matter reduced the fetal weight and length, but increased the number of embryonic resorptions.

Keyword :

Particulate matter, Congenital disorder, Resorbtion, Placenta,


References :

Berkowitz, G.S., M.S. Wolff, T.M. Janevic, I. Holzman, R. Yehuda, and P. Landrigan,(2009) The World Trade Center disaster and intrauterine growth restriction USA : Journal of the American Medical Association. 290(5): 595–6.

Dejmek, J., S.G. Selevan, I. Benes, I. Solansky, and R.J. Sram,(1999) Fetal growth and maternal exposure to particulate matter during pregnancy USA : Environmental Health Perspectives 107 (960): 475-80

Garza, K.M., K.F. Soto, and L.E. Murr,(2008) Cytotoxicity and reactive oxygen spesies generation from aggregated carbon and carbonaceous nanoparticulate materials USA : International Journal of Nanomedicine. 3 (1): 83-94





Archive Article

Cover Media Content

Volume : 7 / No. : 1 / Pub. : 2014-02
  1. Grant Of Ethanol Extract Of Seeds Papaya (carica Papaya) In Female Rats (rattus Novergicus) Antifertilitas Material, As An Alternative To Number And Quality Of Egg Cells
  2. Effect Of Infusum Salam Leaves (eugenia Polyantha) On Blood Glucose Level On The Rat (rattus Norwegicus) In Alloxan Induced
  3. Potential Of Phytase Ezymes From Rumen Bacteria On Sem Analysis Structural Changes Of Rice Bran As Broiler Feed
  4. The Comparison Of Morphology Between Bovine Oocyte Vitrification Before And After In Vitro Maturation
  5. The Effect Of Exposing Pregnant Rat (rattus Novergicus) To Particulate Matter On Congenital Disorder And Resorption Of Embryos
  6. Ha Gene Phyloanalysis Of Influenza H1n1 2009 Virus In Surabaya
  7. Effect Of Seminal Plasm Of Cow On Goat’s Spermatozoa Plasma Membran In Milk Diluter On Semen Freezhing
  8. Histopathological View Pyramid Cell On Cerebrum Of White Rat (rattus Norvegicus) Were Exposed With Methylmercury Which Administrated With Cdp-choline As Neuroprotective Agent
  9. Giving Epigallocathechin Gallate (egcg) Toward The Expression Of Estrogen Receptor At Female White Mouse (rattus Norvegicus)
  10. Human Resource Management Goad Farm Of The Cross Breed Etawa Goat Independent Farm, Farmer Groups And Businesses In The Town Of Turi Sleman Regency
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  12. Potential Mycotoxin Binders On Histopathology Of The Mammary Gland Experiencing Neoplasia In Pregnant Mice (mus Musculus) With Exposed Zearalenone
  13. Potential Of Mycotoxin Binders On Weight And Length Of Fetus Pregnant Mice (mus Musculus) With Zearalenone Exposure
  14. Prevalence Of Worm Disease In Cattle Gastrointestinal Peranakan Ongole (po) And Simental Cattle In The Subdistrict Laren, District Lamongan
  15. The Giving Of Anti- Toxoplasma Gondii Membran Immunoglobulin Y Before Infection Reduce Apoptotic Index Liver Mice

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