UNIVERSITAS AIRLANGGA



Detail Article

Journal of Basic Medical Veterinary

ISSN 2302-6820

Vol. 6 / No. 2 / Published : 2017-12

Order : 7, and page :128 - 135

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Original Article :

Hepatoprotective potency of tomato pasta (lycopersicon esculentum) against histopathological appereance of mice (mus musculus) liver exposed to borax

Author :

  1. Puput Ade Wahyuningtyas *1
  2. Djoko Legowo*2
  3. Wurlina*3
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Dosen Fakultas Kedokteran Hewan

Abstract :

The purpose of this research was to evaluate the hepatoprotective potency of tomato paste (Lycopersicon esculentum) against histopathological appereance  of mice (Mus musculus) liver  exposed to borax. Twenty four mice (Mus musculus) with 60-90 day ages  and 20 g avarage of body weight  were divided into six groups (P0 , P1, P2, P3, P4, and P5). P0 was treated with sterile aquadest 0,1 ml/20g Bw/day, P1 was treated with borax 7,5 mg/20g Bw/day, P2 was treated with tomato paste 300mg/20g Bw/day, P3 was treated with tomato paste 150mg/20g Bw/day and borax 7,5 mg/20g Bw/day, P4 was treated with tomato paste 300mg/20g Bw/day and borax 7,5 mg/20g Bw/day, and P5 was treated with tomato paste 450mg/20g Bw/day and borax 7,5 mg/20g Bw/day. This research has been conducted for 14 days. The data of histopatological appereance were analyzed with Kruskal-Wallis and continued with Man-Whitney. Result  showed there were significant (p<0.05) different between   treatment groups.  This research concluded that tomato paste with dose 450mg/20g BB daily can prevent the damage of hepar that exposed to borax.

Keyword :

Borax, Hepar, Tomato, Paste,


References :

Guyton, A.C., dan Hall, J.E,(2008) Buku Ajar Fisiologi Kedokteran Edisi 11 : EGC

Arab, L. and S. Steck,(2000) Lycopene and Cardiovaskular Disease 71 : 1691-1695 : American Journal of Clinical Nutrition

Dahrul, S., M. Ghaisani, Suratmono, R.A. Sparringa dan N.S. Palupi,(2015) Akar Masalah Keamanan Pangan Jajanan Anak Sekolah: Studi Kasus pada Bakso, Makanan Ringan, dan Mi Vol. 2 (1): 18-25 : Jurnal Mutu Pangan





Archive Article

Cover Media Content

Volume : 6 / No. : 2 / Pub. : 2017-12
  1. Critical Percentages By Adding Alcohol 70% Toward Water In Oil Cream
  2. Protective Effect Of Propolis Extract On Histopathological Features Of Mice’s (mus Musculus) Liver Induced By Lead Acetate
  3. Most Probable Number Of Escherichia Coli On Beef Of Cattle At Krian Sidoarjo Abattoir
  4. The Effect Of Ginger Juice (zingiber Officinale) On Milkfish (chanos Chanos) Total Bakterial
  5. Analysis Of Helminthiasis On Sumatran Tiger (panthera Tigris Sumatrae) In Gunung Bayan Lestari Zoo At West Kutai District East Borneo
  6. The Influence Of Tomato Paste (lycopersicon Esculentum) Administration Against To The Number Of Leydig Cells Of Mice (mus Musculus) Exposed To Borax
  7. Hepatoprotective Potency Of Tomato Pasta (lycopersicon Esculentum) Against Histopathological Appereance Of Mice (mus Musculus) Liver Exposed To Borax
  8. Effect Different Concentration Of Ethanol Extract Tree Marigold (tithonia Diversifolia (hemls.) A. Gray) Leaves Against Candida Albicans
  9. The Effect Of Spirulina Platensis Extract On Histopatology Of White Male Rats (rattus Norvegicus) In Oxidative Stress
  10. Rat’s Algor Mortis In Room With Ambient Temperature And Room With 20°c Temperature
  11. Pengaruh Pemberian Ekstrak Bawang Bombay (allium Cepa L.) Terhadap Tikus Putih Penderita Diabetes Mellitus
  12. Potential Protection Of Tomato Paste (lycopersicon Esculantum) Against Kidney Histopathologic Picture Of Mice (mus Musculus) Exposed To Borax

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