Journal of Basic Medical Veterinary
ISSN 2302-6820
Vol. 6 / No. 2 / Published : 2017-12
Order : 6, and page :120 - 127
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Original Article :
The influence of tomato paste (lycopersicon esculentum) administration against to the number of leydig cells of mice (mus musculus) exposed to borax
Author :
- Vandio Marchenda Praharjaya *1
- Djoko Legowo*2
- Adi Prijo Rahardjo *3
- Mahasiswa Fakultas Kedokteran Hewan
- Dosen Fakultas Kedokteran Hewan
- Dosen Fakultas Kedokteran Hewan
Abstract :
The purpose of this research was to evaluate the influence of tomato paste (lycopersicon esculentum) administration against to the number of leydig cells of mice (mus musculus) exposed to borax. Twenty four male mice (Mus musculus) 60-90 days old with avarage body weight 20 g were used. These animals were divided into six groups (P0, P1, P2, P3, P4, and P5). P0 was treated with sterile aquadest 0,1ml/20g Bw/day, P1 was treated with borax 7,5mg/20g Bw/day, P2 was treated with tomato paste 300mg/20g Bw/day, P3 was treated with tomato paste 150mg/20g Bw/day and borax 7,5mg/20g Bw/day, P4 was treated with tomato paste 300mg/20g Bw/day and borax 7,5mg/20g Bw/day, and P5 was treated with tomato paste 450mg/20g Bw/day and borax 7,5mg/20g Bw/day. This research has been conducted for 14 days. The data were compared using ANOVA and Duncan test by SPSS 22.0 for windows. The result showed that tomato paste 300mg/20g BB daily can prevent the damage of leydig cells in testis that exposed to borax significantly (p<0,05).
Keyword :
tomato, paste, borax, leydig cells,
References :
Adinugroho, N,(2013) Pengaruh Pemberian Boraks Dosis Bertingkat Terhadap Perubahan Gambaran Makroskopis dan Mikroskopis Hepar Selama 28 Hari (Studi pada Tikus Wistar) - : Jurnal Media Medika Muda KTI. Universitas Diponegoro
Soenardirahardjo, B.P., Widjiati, Maslichah, M., Epy, M.L,(2006) Buku Ajar Embriologi - : Airlangga University Press. Surabaya
Kusriningrum, R. S,(2008) Perancangan Percobaan - : Airlangga University Press. Surabaya
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