VetMedika Jurnal Klinik Veteriner
ISSN 2302-6499
Vol. 3 / No. 1 / Published : 2014-07
Order : 4, and page :11 - 14
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Original Article :
The effect of green cincau leaves extract (cyclea barbata l. miers) for total fibroblast and density of collagen on mice's skin
Author :
- Tika Aulia Putri*1
- Chairul Anwar*2
- R. Budi Utomo*3
- Mahasiswa Fakultas Kedokteran Hewan
- Dosen Fakultas Kedokteran Hewan
- Dosen Fakultas Kedokteran Hewan
Abstract :
This research was conducted to investigate the ability of green cincau leaves (Cyclea barbata L. Miers) effect as a medicinal plant for wound healing incision on mice. Twenty of two-three months old male mice with 25 gram average body weight was divided into five treatment groups, a treatment control (P0), positive control (P1) was given povidone iodine 10%, P2, P3, P4 was given concentration 40%, 60%, 80% of green cincau leaves extract. Each treatment consisted of four mice. The experimental design used in this study was completely randomized design (CRD). The data were analyzed using Anova then followed Duncan test and Kruskal-Wallis Statistic Method and then followed by Mann Whitney test with a significance of 5%. The result showed the effect of green cincau leaves extract concentration 80% could increase the number of fibroblasts and collagen fiber density
Keyword :
Incision wounds, green cincau leaves extract, fibroblast, collagen,
References :
Prabawati, N,(2013) Aplikasi ekstrak kulit kelengkeng pada luka pencabutan gigi marmut terhadap jumlah sel fibroblas. Surabaya : Skripsi. Fakultas Kedokteran Gigi. Universitas Airlangga
Sanjaya, M.L.,(2010) Efektifitas ekstrak cincau hijau (Cyclea barbata L. Miers) terhadap penyembuhan luka kronis. Surabaya : Skripsi. Fakultas Kedokteran Gigi. Universitas Airlangga.
Yoyada, N,(2011) Pemanfaatan ekstrak daun sereh (Cymbopogon citratus) terhadap kecepatan penyembuhan luka sayat. Surabaya : Skripsi. Fakultas Kedokteran Gigi. Universitas Airlangga
Wibawati, P.A.,(2012) Pengaruh ekstrak daun sirih merah (Piper betle Var.Rubrum) terhadap waktu kesembuhan luka insisi yang diinfeksi Staphylococcus aureus pada tikus putih Surabaya : Skripsi. Fakultas Kedokteran Gigi. Universitas Airlangga
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