UNIVERSITAS AIRLANGGA



Detail Article

Majalah Ilmu Faal Indonesia

ISSN 0215-1995

Vol. 6 / No. 2 / Published : 2007-02

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Original Article :

Aksi biologi reseptor estrogenα

Author :

  1. Nurul Mahmudati*1

Abstract :

Classical mechanism of estrogen receptor (ERs) action is well known, The classical mechanism of ERs action involves estrogen binding to receptor in the nucleus (nuclear receptor). After binding with receptor in the nucleus these complexes attach to specific DNA response element known as estrogen response element (EREs) that located in the promoters of target gene. The classical mechanism is called as genomic action.. Recent studies show that data regarding estrogen-triggered rapid signaling response independent of nuclear localization. ERs can also regulated gen expression without directly binding to DNA. These have been reffered to as non genomic action . Because of the mechanism initiated from the plasma membrane so called membrane initiated estrogen response. In this article, we will review the genomic action and the evident for plasma membrane ERs initiated estrogen response that called as non genomic action.

Keyword :

ER α, extranuclear receptor, non genomic action ,


References :

Levin,(2001) Genome and Hormonres Gender Different in Physiology: Invited Review: Cel Localization,physiology,and non genomic actions of Estrogen Receptors - : JAppl Physiol

MA Almeida,(2006) Clasical Genotropic Versus Kinase Initiated Regulation of Gene Transkription by the Estrogen Receptor α . - : Endocrinology Vol 147 (4)

L Han,(2006) Clasical Genotropic Versus Kinase Initiated Regulation of Gene Transkription by the Estrogen Receptor α . - : Endocrinology Vol 147 (4)

CAO Brien,(2006) Clasical Genotropic Versus Kinase Initiated Regulation of Gene Transkription by the Estrogen Receptor α . - : Endocrinology Vol 147 (4)

S Kousteni,(2006) Clasical Genotropic Versus Kinase Initiated Regulation of Gene Transkription by the Estrogen Receptor α . - : Endocrinology Vol 147 (4)

SC Monologas,(2006) Clasical Genotropic Versus Kinase Initiated Regulation of Gene Transkription by the Estrogen Receptor α . - : Endocrinology Vol 147 (4)




Archive Article

Cover Media Content

Volume : 6 / No. : 2 / Pub. : 2007-02
  1. Phytoestrogens As Promoters And Protectors Of Breast Cancer
  2. Protein Gzp3 Sebagai Kandidat Bahan Imunokontrasepsi Dikenali Oleh Serum Wanita Fertil Dengan Analisis Elisa Dan Dot Blot
  3. Aksi Biologi Reseptor Estrogenα
  4. Pengaruh Dosis Latihan Fisik Aerobik Terhadap Penurunan Indeks Massa Tubuh, Asam Lemak Bebas Darah Dan Kadar Leptin Darah Pada Mahasiswi Universitas Negeri Semarang
  5. Pengaruh Kekuatan Lengan, Ketebalan Lemak, Dan Body Mass Index Terhadap Prestasi Renang Gaya Crawl 50 Meter
  6. The Metabolic Effect Of Progesterone: Magnificent Phenomenon In Glucose Metabolism And Insulin Regulation During Pregnancy
  7. Peroxisome Proliferator-activated Receptor (ppar)

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