Majalah Obstetri & Ginekologi
ISSN 0854-0381
Vol. 19 / No. 2 / Published : 2011-05
Order : 2, and page :63 - 68
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Original Article :
Comparison between early-onset and late-onset preeclampsia by echocardiographic examination of cardiac output, total vascular peripheral resistance, and doppler velocimetry examination of uterine artery resistance index
Author :
- Muhammad Ilham Aldika Akbar*1
- Erry Gumilar Dachlan*2
- Mahasiswa Fakultas Kedokteran
- Dosen Fakultas Kedokteran
Abstract :
Preeclampsia is still a leading caused (15-20%) of maternal death in developing country. Clinical manifestation of Preeclampsia can have a wide spectrum, from mild disease until severe disease that caused maternal death. From advanced observation, it is found that clinical manifestation of the disease is worst when preeclampsia manifest earlier. It raise the view that onset of the disease is one of the main factor of this difference. Recent view subclassifice Preeclampsia based on onset of clinical manifestation, Early-onset preeclampsia (<34 weeks) and Late-onset preeclampsia (>34 weeks). The objective of this study was to evaluate and compare uterine artery resistance index, cardiac output, and total peripheral vascular resistance value between early-onset and late-onset preeclampsia. This was a cross-sectional observational analytic study was performed at Departement Obstetry and Gynecology Soetomo Hospital, between Desember 2010-June 2011.We analyzed 17 severe preeclampsia pregnant women and 20 normal pregnant women matched by gestational age and inclution and exclution criteria. The Preeclampsia group was divided become two groups, early onset preeclampsia (< 34 weeks) andlate onset preeclampsia (> 34 weeks) based on gestational age during onset of the disease. We examine using doppler velocimetry ultrasound and echocardiography in 1-2 days after the patient admited to hospital. Primary outcome included uterine artery resistance index, cardiac output, and total peripheral vascular resistance value. In conclusion, early onset preeclampsia has higher cardiac output and uterine artery resistance index, and lower total vascular peripheral resistance than late-onset preeclampsia. (MOG 2011;19:63-68)
Keyword :
Early-onset preeclampsia, late-onset preeclampsia, doppler velocimetry, uterine artery resistance index, echocardiography,
References :
Bosio PM, McKenna PJ, Conroy R, O’Herlihy C,(1999) Maternal Central Hemodynamics in Hipertensive Disorders of Pregnancy - : Journal of Obstet Gynecol
Coleman MAG, McCowan LME, North RA,(2000) Mid-trimester Uterine Artery Doppler Screening as A Predictor of Adverse Pregnancy Outcome in High-risk Women - : J of Ultrasound Obstet Gynecol
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