Jurnal Rekonstruksi & Estetik
ISSN 2301-7937
Vol. 2 / No. 1 / Published : 2013-01
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Original Article :
Effectivity of topical chitosan on exudative chronic wound management
Author :
- Rahmat Dianto*1
- M. Sjaifuddin Noer*2
- mahasiswa
- dosen
Abstract :
Background : Wound healing is a complex process which remains a major problem for clinicians, especially for the plastic surgeon who is often a reference to a complex problem and prolonged wound. On chronic wound, there is failure to achieve expected healing within a certain time to produce a recovery of the integrity of the anatomy and function, healing process is slowed or stopped and the wound is not decline in size and depth. Problems usually happened are excessive exudate, infection, and necrotic tissue. Chitosan serves as the absorbent, have stimulatory effect on wound healing and hemostasis, proven to stimulate the production of growth factor and modulate the inflammatory response in wound healing process. Chitosan also induces hemostasis which will stimulate the blood clot in the wound naturally occurring so as to minimize bleeding and close the nerve endings to reduce pain. Over time this material will be broke down by body enzymes into oligomers and monomers of glucosamine that initiate proliferation of fibroblasts, collagen, and helps the disposition of natural hyaluronic acid, which in turn helps to reduce scars and improves wound healing. Purpose : Assess the healing process of exudative chronic wounds with a modified wound bed score on treatment with topical chitosan. Method : 32 patients with exudative chronic wound, excluding them which diagnosed sepsis or MODS, and systemic diseases that can alter the wound healing, are included in this design. Initial management for wounds is applied, followed by assessing the initial modified wound bed score. Topical chitosan is applied on the first day. Topical chitosan is being replaced every 3 days and if necessary due to excessive exudate, bleeding, or secondary infection, time can be less specified. Second assessment of modified wound bed score is held on the tenth day. Total value is classified into four quartiles, 4 to 9, 10 to 11, 12, and 13 to 16. Increase in value from one quartile to the next quartile has increased the clinical relevance of healing around 22.8%. This shows the higher value of the wound score means the better the process of wound healing that occurs. Parameters assessed according to the modified wound bed score are documented digitally. The data will then be analyzed statistically.
Keyword :
Exudative chronic wound, chitosan, modified wound bed score,
References :
Perdanakusuma D.S,(1998) Skin Grafting Surabaya : Airlangga University Press
Sjaifuddin M,(2011) Retrospective Study of Pressure Sores Based on Wound Management of Modern dressing or Traditional Dressing. Surabaya : Airlangga University
Cohen I.K., Diegelmann R.F., Yager D.R., Wornum I.L., Graham M.F., Crossland M.C,(0000) Wound Care and Wound Healing. In : Schwartz S.I., Shires G.T., Spencer F.C., Daly J.M., Fischer J.E., Galloway A.C., editors. Principles of Surgery. 7th ed New York : Mc-Graw Hill
Li L.H., Deng J.C., Deng H.R., Liu Z.L., Li X.L ,(2010) Preparation, characterization and antimicrobial activities of chitosan Ag ZnO blend films London : Chem Eng J
Archive Article
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 Volume : 2 / No. : 1 / Pub. : 2013-01 |
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