UNIVERSITAS AIRLANGGA



Detail Article

Veterinaria Medika

ISSN 1979-1305

Vol. 5 / No. 1 / Published : 2012-02

Order : 13, and page :57 - 62

Related with : Scholar   Yahoo!   Bing

Original Article :

Fluctuation of interleukin-4 ( il-4) in serum and reproductive organ at toxoplasma gondii infected pregnant mouse

Author :

  1. Mufasirin*1
  2. Suprihati, Endang*2
  3. Wayan, T.A*3
  4. Sumartono*4
  1. Fakultas Kedokteran Hewan Universitas Airlangga
  2. Fakultas Kedokteran Hewan Universitas Airlangga
  3. Pusat Studi Bioteknologi, Universitas Gadjah Mada
  4. Pusat Studi Bioteknologi, Universitas Gadjah Mada

Abstract :

The research was aimed to get immune response bases of Toxoplasma gondii through study of interleukin-4 (IL-4) expression in serum and reproductive organ at pregnant mouse which playing a part incongenital infection process. Balb/c mice at twelve weeks old were matched using induction of PMSG and HCG. After gestation, Mice divided to become 3 treatment groups which is infection with T. gondii at first, second and third trimester with control. Three days after infection of mice sacrificed, serum and reproductive organ used as sample. Measurement of expression of IL-4 at serum and reproductive organ by ELISA. Results of research showed expression of IL-4 at serum of mice pregnant at first, second and third trimester, three days after infection T. gondii respectively 0.159, 0.162 and 0.156, and at reproductive organ 0.175,0.204 and 0.193. Expression pattern of IL-4 is enhancement of at second trimester and experience ofreduction at third trimester. There are correlation between expression of IL-4 at serum with at reproductive organ. Enhancement of IL-4 and positive correlation enable happened congenital infection at T. gondii infection.

Keyword :

Toxoplasma gondii, Interleukin-4, Congenital toxoplasmosis,


References :

Beamen MH., CA. Hunter and JS. Remington.,(1994) Enhancement of intracellular replication of Toxoplasma gondii by IL-6 interactions with interferon gamma and TNF . United States : J. Immunol. 153: 4583-4587.

Nagineni, C.N., B. Detrick and J.J. Hooks.,(2002) Transforming growth factor-beta in human retinal pigment epithelial cell is enhanched by Toxoplasma gondii : a possible role in the immunopatholo genesis of retinochoroiditis. United States : Clin. Exp. Immun. 128 (2): 372-378.





Archive Article

Cover Media Content

Volume : 5 / No. : 1 / Pub. : 2012-02
  1. Feed Convertion And Feed Consumption Of Feed Formulation With Different Protein Content
  2. The Potential Of Complete Feed Fermentation Use Cellulolityc Bacteria To Increase Daily Gain Of Sheep
  3. The Effectivity Of Psidium Guajava Linn Leaf Dipping To Chicken Egg Yolk Quality
  4. The Role Of Location Against Gastrointestinal Nematodosis On Cattle At West Madura
  5. The Activity Test Of Whole Bacterium Suspension Of Bacillus Thuringiensis Subspecies Israelensis Serotype H-14 At Mosquito Of Culex Fatigans Pipiens And Aedes Aegypti
  6. The Metabolite Levels Of Broiler Serum That Suffer Due To Warming Heat Stress In The Long Term
  7. Supplement Of Acrosin To The Post Thawing Sperm Of Half-breed Of Etawa Goat (pe) Towards Increasing Potency Of Spermatozoa
  8. Quality Test Of Frozen Semens Of Fat-tailed Sheep In Three Different Kinds Of Semen Extenders
  9. The Level Of Progesteron In Blood Sera Cows Using Ria( Radio Immuno Assay ) After Progesteron Transvaginal Mpa (medroxy Progesteron Acetate)
  10. Model Plastik T Sponge Mpa (medroxy Progesteron Acetate) Soft Release For Oestrus Synchronization In Cows
  11. Eimeria Necatrix Pathogenicity Attenuation Through A Serial Passage Of Precocious Lines Towards Small Intestine Histopathology In Broiler
  12. The Effect Of Ethanol Extracted Of Curcuma Aeruginosa Roxb Rizhoma Toward Degree”s Of Kidney Damage Chicken Layer Which It Is Infected By Ascridia Galli
  13. Fluctuation Of Interleukin-4 ( Il-4) In Serum And Reproductive Organ At Toxoplasma Gondii Infected Pregnant Mouse
  14. Expression Difference Of Αvβ3 In The Endometrium After The Administration Clomiphene Citrate, Combination Of Clomiphene Citrate And Metformin, Or Metformin
  15. A Comparison Of The Effect Melatonin And Forbetes On Blood Glucose Level In Rat (rattus Norvegicus) Experimentally Diabetic Mellitus Type 1

Information index.php/JIPK/tmp_tumb/images/VETMED