Veterinaria Medika
ISSN 1979-1305
Vol. 7 / No. 1 / Published : 2014-02
Order : 6, and page :37 - 42
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Original Article :
Ha gene phyloanalysis of influenza h1n1 2009 virus in surabaya
Author :
- Ema Qurnianingsih*1
- Kadek Rachmawati*2
- Reviany V. Nidom*3
- C.A Nidom*4
- AIRC Universitas Airlangga
- Dosen Fakultas Kedokteran Hewan
- AIRC Universitas Airlangga
- Dosen Fakultas Kedokteran Hewan
Abstract :
Influenza H1N1 2009 virus is a type A influenza virus that caused influenza pandemic in 2009. As of August 1, 2010, data from WHO stated that this virus has spread in 214 countries including Indonesia with more than 18.000 deaths. Although the case fatality rate (CFR) of this virus is low (0,98 %) but it is highly contagious. The first isolate of influenza H1N1 2009 virus is A/California/04/2009, which its genetic analysis revealed that this virus is a triple reassortant virus (from swine influenza virus, avian influenza virus and human influenza virus). It makes this new H1N1 subtype virus is notknown by human immune system. Indonesia, as one the infected country, has no molecular data about this virus yet. Phyloanalysis conducted in this research showed that virus obtained from Surabaya (A/Indonesia/Unair/2010) had similarity with influenza H1N1 2009 virus in Perth, Australia, (A/Perth/260/2009).
Keyword :
Influenza H1N1 2009 virus, Surabaya, Phyloanalysis,
References :
Itoh Y., K.Shinya, M. Kiso, T. Watanabe, Y. Sakoda, M. Hatta, Y. Muramoto, D. Tamura, Y. Sakai-Tagaw,(2009) In vitro and in vivo characterization of new swine origin H1N1 influenza viruses . : Nature. 460: 1021-1025
Puzelli S., M. Facchini, D. Spagnolo, M.A. De Marco, L. Calzoletti, A. Zanetti, R. Fumagali, M.L. Ta,(2010) Transmision of hemaglutinin D222G Mutant Strain of Pandemic (H1N1) 2009 Virus . : Emerging Infectious Diseases . 16(5) : 863-865
Novel swine-origin investigation team,(2009) Emergence of novel swine-origin influenza virus (H1N1) in human . : NEJM. 360:2605-2615
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