UNIVERSITAS AIRLANGGA



Detail Article

Planta Husada

ISSN 2338-7130

Vol. 1 / No. 1 / Published : 2013-10

Order : 3, and page :7 - 9

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Original Article :

Hypoglycemic activity of andrographis paniculata nees. and lagerstroemia speciosa l. herbal tea combination

Author :

  1. Aty Widyawaruyanti*1
  2. Sukardiman*2
  3. Mulja Hadi S*3
  4. Iqbal Aya S*4
  1. Dosen Fakultas Farmasi
  2. Dosen Fakultas Farmasi
  3. Dosen Fakultas Farmasi
  4. Mahasiswa Fakultas Farmasi

Abstract :

Hypoglycemic Activity of Andrographis paniculata Nees. and Lagerstroemia speciosa L. Herbal Tea Combination.  Aty Widyawaruyanti*), Sukardiman, Mulja Hadi S., Iqbal Aya S.  Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy Universitas Airlangga, Surabaya, Indonesia.   *)email : aty_ww@yahoo.com  The combination of Andrographis paniculata Nees and Lagerstroemia speciosa L. herbal tea was evaluated in alloxan-induced diabetic mice, due to andrographolide and corosolic acid that have known for its hypoglycemic effect. This study aimed to find out that combination of Andrographis paniculata Nees and Lagerstroemia paniculata L. herbal tea will have better hyplogycemic effect than single prepration. Alloxan monohydrate (150mg/kg BW) intraperitoneally to make hyperglycemia condition in mice. Glibenclamide (0.013 mg/20g BW) used as control positive and the suspension of CMC-Na 0.5% as control negative. Oral administration of herbal tea (0.4ml/20g BW) was given to 5 groups (Andrographis paniculata Nees, Lagerstroemia paniculata L. and both combination with ratio 2:1, 1:1 and 1:2) for 7 days. The result is all group of herbal tea have hypoglycemic effect. Andrographis paniculata Nees. showed the biggest reduction in BGL (75.20±133.00 mg/dL) than the other herbal tea groups. Data obtained was subjected to annova one-way analysis of variance followed by Tukey test to determine the statistical significance of the change in BGL. Only control positive that has significant difference with Negative control groups (P < 0.05).  

Keyword :

Andrographis paniculata, Lagerstroemia speciosa, Hypoglycemic activity, Herbal tea,


References :

Anonim,(2008) Riset Kesehatan Dasar 2007 Jakarta : Departemen Kesehatan Republik Indonesia

Hossain MA et al.,(2007) Antidiabetic Activity of Andrographis paniculata - : Dhaka Univ. J. Pharm. Sci

Handa SS et al.,(2008) Extraction Technologies for Medicinal and Aromatic Plants - : International Centre For Science And High Technology

Katzung BG,(2010) Farmakologi Dasar dan Klinik. Edisi XI New York : McGraw Hill

Saha BK et al.,(2009) Hypoglycemic activity of Lagerstroemia speciosa L. extract on streptozotocin-induced diabetic rat: Underlying mechanism of action - : Bangladesh Journal of Pharmacology





Archive Article

Cover Media Content

Volume : 1 / No. : 1 / Pub. : 2013-10
  1. Hypoglycemic Activity Of 96% Ethanolic Extract Of Andrographis Paniculata Nees. And Swietenia Mahagoni Jacq. Combination.
  2. Hypoglycemic Activity Herbal Tea Combination Of Andrographis Paniculata Herbs And Swietenia Mahagoni Seeds
  3. Hypoglycemic Activity Of Andrographis Paniculata Nees. And Lagerstroemia Speciosa L. Herbal Tea Combination
  4. ¬hypoglycemic Activity Of The Herbal Tea Combination Of Bitter Melon (momordica Charantia L.) And Lagerstroemia Speciosa Leaves In Alloxan-induced Mice
  5. Hypoglycemic Effect Of Andrographis Paniculata Nees And Lagerstroemia Speciosa Extract Combination

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