Planta Husada
ISSN 2338-7130
Vol. 1 / No. 1 / Published : 2013-10
Order : 4, and page :10 - 12
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Original Article :
¬hypoglycemic activity of the herbal tea combination of bitter melon (momordica charantia l.) and lagerstroemia speciosa leaves in alloxan-induced mice
Author :
- Idha Kusumawati*1
- Sukardiman*2
- Herra Studiawan*3
- Abdul Rahman*4
- Mulja Hadi S*5
- Evan Susandi*6
- Dosen Fakultas Farmasi
- Dosen Fakultas Farmasi
- Dosen Fakultas Farmasi
- Dosen Fakultas Farmasi
- Dosen Fakultas Farmasi
- Mahasiswa Fakultas Farmasi
Abstract :
The aim of this study is to evaluate the hypoglycemic activity of the herbal tea combination of Momordica charantia L. and the leaves of Lagerstroemia speciosa in alloxan-induced diabetic mice. Hypoglycemic activity of the herbal tea (0.4 ml/20 g body weight) was tested in five groups of Balb/C mice with at least five animals each and the results were statistically compared with the results of CMC-Na 0.5% (negative control) and a known antidiabetic drug glibenclamide 0.013 mg/20 g body weight. Oral administration the herbal tea of M.charantia and its combination with L.speciosa leaves in ratio (2:1), (1:1), and (1:2) for 7 days exhibited significant reduction of blood glucose level in alloxan-induced diabetic mice.
Keyword :
Hypoglycemic activity, Momordica charantia , Lagerstroemia speciosa, Herbal Tea,
References :
Berawie N,(2004) Inventory, Documentation and Status of Medicinal Plants Research in Indonesia. di dalam Batugal, Pons A, Jayashree K, Lee Sok Y dan Jeffrey T (ed.), Medicinal Plants Research in Asia. Malaysia - : International Plant Genetic Resources Institute
Handa SS et al.,(2006) Compendium of Medicinal and Aromatic Plants Asia - : United Nations Industrial Development Organization and the International Centre
Klein G et al.,(2007) Antidiabetes and Anti-obesity Activity of Lagerstroemia speciosa - : Advance Access Publication
Krawinkel MB and Keding GB,(2006) A Dietary Approach to Hyperglycemia - : International Life Sciences Institute
Kumar SR et al.,(2011) Momordica charantia Linn. A Mini Review - : International Journal of Biomedical Research
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