UNIVERSITAS AIRLANGGA



Detail Article

Journal Of Emergency

ISSN 2301-7864

Vol. 2 / No. 1 / Published : 2013-07

Order : 6, and page :36 - 42

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Original Article :

Effect of enteral glutamine supplementation for the low birth weight on gaining weigh pattern and level of faecal secretory iga

Author :

  1. Mahendra Sampurna*1
  2. Nur Aisiyah Wijaya*2
  1. Mahasiswa Fakultas Kedokteran
  2. Dosen Fakultas Kedokteran

Abstract :

Background: Extrauterine growth retardation, immune deficiency is a major problem of low birth weight (LBW). Babies have a biphasic pattern in growing weight loss before after. It is essential for LBW to achieve growth spurt equal to or greater than intrauterine growth, glutamine plays a role in the catabolic phase, stimulates protein synthesis to optimize growth, besides glutamine as fuel for the immune system, especially in the enterocytes of the gut mucosal immune responses. Purpose: To prove the effect of enteral glutamine supplementation on gaining weight pattern and faecal secretory IgA Method: A double blind randomized control trial. Two groups assin as glutamine and placebo group. Glutamine group receives breastfeed, and preterm formula supplementation with glutamine 400 mg/kg/d for 14 d was observed 30 d, placebo supplementation with glucose. Monitoring of return to birth weight, gaining weight velocity and level of faecal secretory IgA. Results: 37 LBW infants (1500-2499 g) were randomly grouped double blind into 18 glutamine group and 19 placebo. Glutamine group had a return to birth weight shorter than placebo (8.1 ± 0.9 vs 11.0 ± 1.6 days) and faster the gaining weight velocity r (20.0 ± 1.8 vs 15.5 ± 2.2 g / kg / day), statistically significant (p = 0.0001). sIgA levels after glutamine supplementation was higher than the placebo group (0.456 ± 0.057 vs 0.376 ± 0.035 mg / g), the difference was statistically significant (p = 0.0001), whereas levels of faecal sIgA of glutamine group 76% higher than placebo. sIgA levels after treatment in each groups of glutamine greater than placebo (0.274 ± 0.024 vs 0.140 ± 0.016 mg / g), was statistically significant (p – 0.0001). Conclusion: Enteral glutamine supplementation in LBW speed return to birth weight, increasing the gaining weight velocity and the levels of faecal secretory IgA.

Keyword :

LBW, enteral glutamine supplementation, gaining weight pattern, faecal sIgA,


References :

Bang A, Reddy MH, Deshmukh MD,(2002) Child mortality in Maharashtra 37:4947-65 : Economic Political weekly





Archive Article

Cover Media Content

Volume : 2 / No. : 1 / Pub. : 2013-12
  1. The Effect Of Hyperthermia As A Remote Hyperthermic Preconditioning (rhp) On Viability Of Random Pattern Skin Flap In Rat
  2. The Effect Of Fat Tissue Mesenchymal Stem Cells To The Total Amount Of Receptor Of Basic Fibroblast Growth Factor (bfgf) In Wound Healing Process On Males Rabbit (oryctolagus Cuniculus)
  3. Effect Of Adipose Mesenchymal Stem Cells On Angiogenesis Process On Rabbit Skin Wound
  4. Lactate Levels, Deficit Bases, And Metabolic Acidosis Measures As Predictors Factor Laparotomy In Patients With Blunt Abdominal Trauma Fast Positive At Emergency Department Of Soetomo General Hospital Surabaya
  5. Relationship Between Intraoculi Pressure, Intracranial Pressure And Mean Arterial Pressure On Severe Brain Injury Patients
  6. Diagnostic Test Of Serum Glial Fibrilary Acidic Protein For Differentiating Intracerebral Hemorrhage Stroke And Non Hemorrhage / Ischemic Stroke In Acute Stroke Patients
  7. Effect Of Enteral Glutamine Supplementation For The Low Birth Weight On Gaining Weigh Pattern And Level Of Faecal Secretory Iga
  8. Correlation Between Body Mass Indeks And Incidence Of Hypotension On Pregnant Mothers Undergoing Caesarean Section Under Spinal Block Anesthesia
  9. Analysis Of The Level Of Rationality Of Blood Tranfusion In Emergency Surgery Serviced In The Emergency Department Soetomo General Hospital Surabaya

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