UNIVERSITAS AIRLANGGA



Detail Article

Journal Of Emergency

ISSN 2301-7864

Vol. 1 / No. 1 / Published : 2011-12

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Original Article :

The effectiveness of ketamine dose 0.25 mg/kg body weight intravenous as a therapy of shivering during spinal anesthesia in sectio caesaria surgery

Author :

  1. Mirza Koeshardiandi*1
  2. Nancy Margarita R*2
  1. Mahasiswa
  2. Dosen

Abstract :

Background: Shivering is one of the complications that often occurs in anesthesia, it especially occurs during and after regional anesthesia or after general anesthesia. Regional anesthesia will produce a pattern of heat loss and hypothermia which are similar to what happens in general anesthesia. Epidural and spinal anesthesia decrease the threshold of vasoconstriction and shivering for about 0.6 OC. Non pharmacologic standard therapies that have been done, still causes shivering in this case. Thus for pregnant women who undergo sectio caesaria and experience shivering, pharmacological therapy is still needed. However, no pharmacological therapies are safe for the fetus that can be given before the baby is born. Objective: Proving that ketamin dose of 0.25 mg/kg body weight, can be used as an effective and safe shivering therapy after spinal anesthesia in sectio caesaria either before or after birth. Design: Intervention studies, double blind method, control group Methods: This study uses intervention studies form with double blind method and control group. Comparing the effectiveness of ketamine and NaCl 0.9% for shivering therapy before the baby is born. And comparing the effectiveness of ketamine and pethidine for the treatment of shivering, after the baby is born. Results: Ketamine intravenous dose of 0.25 mg/kg body weight can decrease shivering significantly (p = 0.000) before the baby is born, and significantly different (p = 0.000) compared to NaCl 0.9%. Comparison of the effectiveness of ketamine and pethidine is not so different with p = 0.07 (p > 0.05). Nevertheless, pethidine is higher in lowering the degree of shivering. Side effects that arise both in the mother or the baby was not significantly different with NaCl 0.9% (control group).

Keyword :

Sectio caesarea, spinal anesthesia, ketamine, shiver,


References :

Wray, Sarah, Plaat, Felicity ,(2007) Regional anaesthesia for caesaran section and what to do when it fails New York : Journal of Anaesthesia and Intensive Care Medicine

Bhattacharya, K. Pradip, Bhattacharya, Latta, Jain, K. Rajnish, Agarwal, Ramesh C ,(2003) Post anesthesia shivering (PAS): A review New Delhi : Indian Journal of Anesthesia





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  7. The In Vitro Changes Of Blood Clotting Factors Of Whole Blood With Viscoelastometry Examination
  8. The Effectiveness Of Ketamine Dose 0.25 Mg/kg Body Weight Intravenous As A Therapy Of Shivering During Spinal Anesthesia In Sectio Caesaria Surgery