UNIVERSITAS AIRLANGGA



Detail Article

Journal of Basic Medical Veterinary

ISSN 2302-6820

Vol. 2 / No. 2 / Published : 2013-12

Order : 8, and page :86 - 89

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Original Article :

In vitro cytotoxic effects of rosella extract (hibiscus sabdariffa) against myeloma cell culture

Author :

  1. Rochmah Kurnijasanti*1
  2. Isa Mahendra*2
  3. Nancy Dahnia*3
  4. Rangga Mung*4
  5. Margaretha*5
  6. Arnold Hutapea*6
  1. Dosen Fakultas Kedokteran Hewan
  2. Mahasiswa Fakultas Kedokteran Hewan
  3. Mahasiswa Fakultas Kedokteran Hewan
  4. Mahasiswa Fakultas Kedokteran Hewan
  5. Mahasiswa Fakultas Kedokteran Hewan
  6. Mahasiswa Fakultas Kedokteran Hewan

Abstract :

This research aims was examined the anticancer activity of rosella extracts (Hibiscus sabdariffa) on myeloma cell culture by myeloma cell viability method. Myeloma cancer cells incubated in medium Rosewell Park Memorial Institute (RPMI) containing 10% fetal bovine serum (FBS). Rosella extract concentration consists of 10%, 20%, 30%, 60%, and 100%. Rosella extract was added to the myeloma cell cultures that had been placed in a microwell plate and incubated for 24 h at 37 ° C with carbon dioxide gas (CO2) 5%. Anticancer activity seen by the MTT Cell Proliferation assay were read by ELISA reader, with optical desity (OD) of the number of dead cells. Data were analyzed by ANOVA and Duncan's multiple range test showed that the rosella extract has the ability to kill myeloma cells.     

Keyword :

Hibiscus sabdariffa, Stomatitis.,


References :

Chang, Y.C., S.F. Chen., S. Nien., C.H. Wu., C.L. Liu, Y.S.Lin.,(2012) . Reappraisal of the Anticancer Efficacy of Quercetin in Oral Cancer Cells. China : Journal of the Chinese Medical Association 76 (2013) 146e152

Didah, N.. ,(2005) Pengaruh Pemberian Seduhan Kelopak Rosella Ungu Terhadap Kadar Kolesterol LDL SerumTikus. Semarang : Program Studi Ilmu Gizi. Fakultas Kedokteran. Uni¬ver¬sitas Diponegoro.





Archive Article

Cover Media Content

Volume : 2 / No. : 2 / Pub. : 2013-12
  1. Ldl Cholesterol Levels Of Male Rats (rattus Norvegicus) After Trans Fatty Acid In Margarine And Shorthening Consumption
  2. The Effect Of Cosmos Caudatus Leaf Ethanol Extract In Liver On Paracetamol Induced Elevation Sgot And Sgpt In Balb/c Mice
  3. Cholesterol Ldl White Mouse (rattus Novergicus) Levels Given Trans Fatty Acids From Margarine, White Butter And Waste Cooking Oil
  4. Time Patern Of Curcuma Zedoaria Etract Against Amount Of Mice Pulmonary Nodules Indusced By Benzo(α)pyrene
  5. The Effect Of Meniran (phyllanthus Niruri Linn) Infusion On Kidney Histopathological Overview Of White Rats (rattus Norvegicus) Exposed By Alkohol
  6. The Effect Of Giving Gossypol In (gossypium Hirsutum) To Cricket As Natural Insect Killer
  7. Antibacterial Potential Of Infusum Salak ( Salacca Zalacca ) To Staphylococcus Aureus And Escherichia Coli An In Vitro
  8. In Vitro Cytotoxic Effects Of Rosella Extract (hibiscus Sabdariffa) Against Myeloma Cell Culture

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