UNIVERSITAS AIRLANGGA



Detail Article

Jurnal Penelitian Medika Eksakta

ISSN 1411-6626

Vol. 7 / No. 1 / Published : 2008-04

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Original Article :

Efek pemberian epinefrin terhadap hemoglobin, jumlah eritrosit dan retikulosit

Author :

  1. Gadis Meinar Sari*1
  2. Sunarko Setyawan*2
  3. Agustina Rahayu M*3
  1. Bagian Ilmu Faal, Fakultas Kedokteran Universitas Airlangga
  2. Bagian Ilmu Faal, Fakultas Kedokteran Universitas Airlangga
  3. Mahasiswa S2 Ilmu Kedokteran Dasar Universitas Airlangga, Bag. Ilmu Faal Unmul

Abstract :

The effect of acute and chronic epinephrin administration on hemoglobin, RBC, , and reticulocyte, remains controversial. Physiological approach is needed to investigate epinephrin's effect on erythrocyte quality. The analysis unit was blood taken directly from heart, and subjected to hemoglobin (g/dl), erythrocyte (106/ul) and reticulocyte examination (cell/103 erythrocyte). Treatment groups received epinephrin subcutaneous injection, and control groups received 0.9% NaCl subcutaneous injection. Data were taken directly after one injection (treatment 1), 30 minutes after one injection (treatment 2), and after 7 days with 6 injections/day (treatment 3). Epinephrin dose was 0.05 mg/200 g BW rats in each injection, and injection volume was 0.5 ml. The results of t-test between the delta of pretest and posttest group were difference (p > 0.05). Manova test between the delta of treatment and control group were not significantly difference (Hotelling's trace, p > 0.05). Univariate test the difference was found in reticulocyte delta (p < 0,05) but hemoglobin and erythrocyte were not significantly difference (p > 0.05). In conclusion: acute epinephrin administration was increasing reticulocyte, while chronic epinephrin administration was decreasing reticulocyte. Hemoglobin and RBC looks like normal.

Keyword :

epinephrine; Hemoglobin; erythrocyte; Reticulocyte,


References :





Archive Article

Cover Media Content

Volume : 7 / No. : 1 / Pub. : 2008-04
  1. Efek Pemberian Epinefrin Terhadap Hemoglobin, Jumlah Eritrosit Dan Retikulosit
  2. Perubahan Oral Flora Dan Sensitifitas Karies Gigi Anak Setelah Pengulasan Fluoride Secara Topikal
  3. Potensi Analgesik Dan Antiinflamasi Dari Ekstrak Tapak Liman (elephantophus Scraber)
  4. Efek Antinociceptif Gaba Agonis Gabapentin Terhadap Nyeri Neuropati Pada Hewan Coba Mencit
  5. Modifikasi Pati Singkong Pregelatin Sebagai Bahan Pembawa Cetak Langsung
  6. Efek Sitotoksik In Vitro Dari Ekstrak Buah Mahkota Dewa (phaleria Macrocarpa) Terhadap Kultur Sel Kanker Mieloma
  7. Pemberian Whole Serum Kuda Lokal Bunting Yang Disentrifugasi Dengan Charcoal Terhadap Birahi Dan Kebuntingan Pada Sapi Potong
  8. Inferensi Kurva Regresi Nonparametrik Berdasarkan Estimator Polinomial Lokal Dengan Error Lognormal
  9. Faktor-faktor Yang Mempengaruhi Perempuan Dalam Menghadapi Menopause
  10. Manipulasi Reproduksi Pada Itik Petelur Afkir Dengan Pregnant Mare Serum Gonadotropin

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