Jurnal Respirasi
ISSN 2407-0830
Vol. 1 / No. 2 / Published : 2015-05
Order : 5, and page :67 - 71
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Original Article :
Biomarker pernapasan pada penyakit paru
Author :
- Novita Maulidiyah, dr*1
- Prof. Dr. Muhammad Amin, dr., Sp.P(K)*2
- Mahasiswa Fakultas Kedokteran
- Dosen Fakultas Kedokteran
Abstract :
Breath analysis provides a convenient and simple alternative to traditional specimen testing in clinical laboratory diagnosis. As such, substantial research has been devoted to the analysis and identification of breath biomarkers. Development of new analytes enhances the desirability of breath analysis especially for patients who monitor daily biochemical parameters. Elucidating the physiologic significance of volatile substances in breath is essential for clinical use. This review describes the use of breath biomarkers in diagnosis of asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF), lung cancer, as well as other pulmonary diseases. A number of breath biomarkers in lung pathophysiology will be described including nitric oxide (NO), carbon monoxide (CO), hydrogen peroxide (H2O2) and other hydrocarbons.
Keyword :
nitric oxide, hidrogen peroxide, pulmonary disease,
References :
Meigu Z, smith AD,(2012) breath biomarker in diagnosis of pulmonary disease - : Clinical Chimica Acta
Raed A, Dweik, Peter B,(2011) interpretation of exhaled NO levels (Feno) for clinical application - : ATS
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