Detail Article

Jurnal Urologi Universitas Airlangga

ISSN 23026480

Vol. 1 / No. 1 / Published : 2013-01

Order : 5, and page :5 - 5

Related with : Scholar   Yahoo!   Bing

Original Article :

Comparison of sextant and 10-core biopsy for the detection of prostate cancer

Author :

  1. Abdul Azis*1
  2. Lukman Hakim*2
  3. Doddy M Soebadi *3
  4. kosong*4
  5. kosong*5
  1. kosong
  2. kosong
  3. kosong
  4. kosong
  5. kosong

Abstract :

Purpose: to compare the sensitivity, specificity, positive predictive value, negative predictive value and accuracy of sextant and 10-core biopsies in detection of prostate cancer. Material and Methods: We collected medical records of patients retrospectively who underwent prostate biopsy between 2005–2009 and performed diagnostic study. Two groups were made by the period of biopsies taken (between 2005–2007 for sextant core, and between 2007–2009 for 10-core which were the standard technique). The percentages of positive cores was calculated and analyzed by a ROC curve.  Results: The data from 660 patients,  353  (53%) underwent sextant core biopsy, while 307 others (47%) had a  10-core biopsy. Thirty patients were diagnosed as high-grade prostatic intra-epithelial neoplasia based on the biopsy, and 6 (20%) from them were confirmed as adenocarcinoma of the prostate based upon the surgical specimen. Sextant core biopsy had a sensitivity, specificity, positive predictive value, and negative predictive value of 70.37%, 98.67%, 82.61%, and 97.37%, respectively. While the 10-core biopsy had a sensitivity, specificity, positive predictive value, and negative predictive value of 91.43%, 99.25%, 94.12%, and 98.88%, respectively. Accuracy of sextant core and 10-core biopsy in the detection of prostate cancer were 84.4% and 95.3%, respectively. Conclusions: In this study, 10-core prostate biopsy technique had a higher accuracy, sensitivity,  specificity, positive predictive value, and negative predictive value than the sextant core for prostate cancer detection, which is the goal of the procedure. These results proof again the superiority of the 10-core biopsy.

Keyword :

prostate cancer, sextant core, 10-core, biopsy, kosong,

References :

Klein, EA, Platz, EA & Thompson, IM ,(2007) Epidemiology, Etiology, and Prevention of Prostate Cancer Philadelphia : WB Saunders

Ramey, JR, Halpern, EJ & Gomella, LG ,(2007) Ultrasonography and Biopsy of the Prostate Philadelphia : WB Saunders

Alavi, AS, Soloway, MS, Vaidya, A, Lynne, CM & Gheiler, EL,(0000) Local Anesthesia for Ultrasound Guided Prostate Biopsy: a Prospective Randomized Trial Comparing 2 Methods kosong : kosong

Naughton, CK, Miller, DC, Mager, DE, Ornstein, DK & Catalon, WJ ,(2000) A Prospective Randomized Trial Comparing 6 Versus 12 Prostate Biopsy Cores: Impact on Cancer Detection kosong : kosong

Presti, JC, Chang, JJ, Bhargava, V & Shinohara, K ,(2000) The Optimal Systematic Prostate Biopsy Scheme Should Include 8 rather than 6 biopsies: Results of a Prospective Clinical Trial kosong : kosong

Archive Article

Cover Media Content

Volume : 1 / No. : 1 / Pub. : 2013-01
  1. Feokromositoma Dengan Trombus Di Vena Cava Inferior
  2. Karakteristik Penderita Hipospadia Yang Dirawat Di Rsup Sanglah Denpasar Periode Januari 2005 - Juni 2007
  3. Placenta Percreta With Bladder Invasion
  4. Correlation Between Psad, Hypoechoic Lesion, And Gleason Score In Patients Undergoing Prostate Biopsy At Dr.sutomo Hospital Surabaya From January – December 2009
  5. Comparison Of Sextant And 10-core Biopsy For The Detection Of Prostate Cancer
  6. Multiple Anomaly Of The Kidney
  7. Conn's Syndrome Due To Adrenal Tumor
  8. Penopubic Epispadias Without Incontinence
  9. Endometriosis Buli
  10. Bilateral Congenital Primary Obstructive Megaureter
  11. Profile Urodinamik Pasien Gangguan Miksi Di Rsu Dr. Soetomo Surabaya
  12. Benda Asing Dalam Buli
  13. Cystographic Undetected Bladder Rupture