UNIVERSITAS AIRLANGGA



Detail Article

Majalah Farmasi Airlangga (Airlangga Journal of Pharmacy)

ISSN 0852-1050

Vol. 5 / No. 3 / Published : 2005-12

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Original Article :

Uji efektifitas sediaan gel antiseptik tangan yang mengandung etanol dan triklosan

Author :

  1. Dewi Isadiartuti*1
  2. Retno Sari*2
  1. Bagian Farmasetika, Fakultas Farmasi Universitas Airlangga
  2. Bagian Farmasetika, Fakultas Farmasi Universitas Airlangga

Abstract :

Alcohol and triclosan are commonly used in hand gels antiseptic preparations. Both substances have deferent mechanism for preventing microorganism growth. The activity of alcohol and triclosan in a dosage form can be inactivated or increased by organic material. The objective of this research is to evaluate the effectiveness of hand gels antiseptic preparations which is widely used in the market. Four different products of hand gels antiseptic preparations which contain ethanol or triclosan as active ingredient were selected (each two products for different active ingredient). The effectiveness of these antiseptic preparations were evaluated by Replica method. In this method 0.5 mL gel was spread over the hand palm, after 60 seconds contact, the thumb fingerprint was slightly tap to the nutrient agar media. The media was incubated at 370.5ºC for 24 hours, and then the colonies were counted. The results showed that triclosan gel preparation could eliminate microorganism up to 89%, while the ethanol gel preparation up to 46%.

Keyword :

antiseptic, ethanol, triclosan, Replica method,


References :

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S.S. Block,(2001) Disinfectant, Sterilization and Preservation, 4nd Edition London : Lea and Febiger

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Archive Article

Cover Media Content

Volume : 5 / No. : 3 / Pub. : 2008-01
  1. Uji Efektifitas Sediaan Gel Antiseptik Tangan Yang Mengandung Etanol Dan Triklosan
  2. Pengembangan Formula Sediaan Gel Antiseptik Tangan Ekstrak Daun Sirih (piper Betle Linn)
  3. Pengaruh Posisi Gugus Metoksi Para Dan Meta Terhadap Hasil Sintesis Asam Para-metoksisinamat Dan Asam Meta-metoksisinamat
  4. Aktivitas Antimalaria Ekstrak Metanol, Fraksi Dan Isolat-isolat Dari Kulit Batang Cempedak (artocarpus Champeden, Spreng.)
  5. Aktivitas Antimalaria Ekstrak Diklorometana Kulit Batang Artocarpus Champeden Pada Kultur Plasmodium Falciparum
  6. Uji Toksisitas Akut Dan Subakut Ekstrak Etanol Dan Ekstrak Air Kulit Batang Artocarpus Champeden Spreng Dengan Parameter Histopatologi Hati Mencit
  7. Pengaruh Ekstrak Etanol Dan Ekstrak Air Kulit Batang Artocarpus Champeden Spreng Terhadap Kadar Enzim Sgpt Dan Sgot Mencit.

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