Majalah Ilmu Faal Indonesia
ISSN 0215-1995
Vol. 5 / No. 1 / Published : 2005-10
Order : 3, and page :18 - 23
Related with : Scholar Yahoo! Bing
Original Article :
Peran fisiologis sekresi leptin sebagai dasar pencegahan obesitas
Author :
- Anwar Ma'ruf*1
- Dosen Fakultas Kedokteran Hewan
Abstract :
The objective of the study is to know the effect of time regulation and the amount of diet administration on leptin secretion as basis to prevent obesity. This was laboratory experimental study using complete randomized design with factorial pattern of 3 x 3, revealing 9 treatment groups with 8 repetitions. Treatment consisted of feeding time 1, 2, and 3 times with standard diet, 10% less and 10% more than standard diet. Serum leptin level examination was done using Elisa, while lipid and protein content in flesh were examined using respectively Soxhlet and Marcam Steel methods. Data were analyzed using analysis of variance (Anova), followed by least significant difference (LSD) test when difference was found. Results showed that serum leptin level, lipid and protein content in murine flesh fed 1 and 2 times a day with standard diet and 10% less than standart diet were significantly different from those in other group (p < 0.05). It can be conciuded that feeding of 1 and 2 times a day with standart and 10% less than standard and 10% less than standard diet result in lower serum leptin and flesh lipid levels and higher flesh protein level
Keyword :
leptin, lipid level, protein level,
References :
Ashwell, C.M., J.P. McMurtry, X.H. Wang, Y. Zhou, and R.V. Younken,(1999) Effect of growth hormone and pair-feeding on leptin mRNA expression in liver and adipose tissue - : Domest. Anim. Endrocrinol, 17: 77-84
Byatt, J.C, N.R. Staten, W.J. Salgiver, J.G. Kostelc, and R.J. Collier,(1993) Stimulation of food in take and weight gain in mature female rats by bovine prolactin and bovine growth hormone. - : Am. J. Physiol, 246:986-992
Archive Article
| Cover Media | Content |
|---|---|
 Volume : 5 / No. : 1 / Pub. : 2005-10 |
|
