Detail Article

Majalah Ilmu Faal Indonesia

ISSN 0215-1995

Vol. 10 / No. 1 / Published : 2010-10

Order : 1, and page :1 - 7

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Original Article :

The effectiveness of guava leaf extract (psidium guajava l.) on erythrocytes superoxide dismutase activity sports treated rattus norvegicus

Author :

  1. Sudarno*1
  1. Dosen Fakultas Kedokteran

Abstract :

The aim of this study study to determine the effectiveness of guava leaf extract on Rattus norvegicus enzyme activity, Superokside dismutase (SOD), which is  given a stressor treatment exercise pool with a load of 9% of body weight of rats. This research uses laboratory experimental research design with the randomized post-test only control group design. There are four groups (group 1, 2, 3 and 4), group 1 (control) were given training pool only, groups 2, 3 and 4 are given training pool and guava leaf extracts with different doses, group 2 doses of 2.724 mg / 200gr BW rats, groups of 3 doses of 5.407 mg / 200gr BW rats and group 4 dose 10.813 mg / 200gr BW rats. Conducted follow-up for 6 days, erythrocyte SOD activity examination conducted on the last day (sixth). Data showed an increase of erythrocyte SOD activity significantly (p = 0.014 or p <0.05) in groups 2, 3, and 4 (P1 = 27.062 ± 0.667, P2 = 28.905 ± 0.777, and P3 = 28.667 ± 0.817) than group control (K = 26.080 ± 2.387). This means that the guava leaf extract for 6 days showed preventive effects against the decrease in erythrocyte SOD enzyme activity is given stressor treatment exercise pool with a load of 9% of body weight of rats.

Keyword :

Guava leaf extract, superokside dismutase (SOD), sports,

References :

Saraf Sw., Ashawat M.S., Saraf Sh,(2007) Flavonoid: A nutritional protection against oxidative and UV induced cellular damages, Institute of pharmacy Vol 1 Issue 1, Jan-May : Pharmacognosy Reviews

Marks D.B., Marks A.D., Smith C.M,(2000) Biokimia kedokteran dasar sebuah pendekatan klinis, Cet.1 hal: 305-313, 321- 3 : Kedokteran EGC

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Volume : 10 / No. : 1 / Pub. : 2010-10
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  12. The Effectiveness Of Guava Leaf Extract (psidium Guajava L.) On Erythrocytes Superoxide Dismutase Activity Sports Treated Rattus Norvegicus