UNIVERSITAS AIRLANGGA



Detail Article

Majalah Obstetri & Ginekologi

ISSN 0854-0381

Vol. 21 / No. 2 / Published : 2013-05

Order : 6, and page :77 - 83

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Original Article :

Viral load pada kanker serviks terinfeksi human papilloma virus tipe 16

Author :

  1. ING Budiana*1
  1. -

Abstract :

The most common cause ofcervical cancer is HPV-16 infection. The integration process between of host DNA and HPV virus DNA depends on the amount ofviral load (VL). The objective of this study was to determine the average and cut off point of VL on cervical cancer with HPV-16 infection. The study design was a case-control study during year of 2010-2011 which performed at Obstetrics& Gynecology Department, Medical Faculty Udayana University and Biomedical Laboratory RSUD Mataram. The diagnose of cervical cancer based on histopatological, HPV-16by PCR and VL HPV-16 by PCR-EIA. The amount of 18samples as a case group of cervical cancer with positive VL HPV-16 and 18 samples as a control group of non-cervical cancer withpositive VL HPV-16. In the both groups, the averageof VL HPV-16 are 2,0 x 107copy/μg and 2,8 x 105copy/μg, respectively. The cut off point of VL HPV-16 is 2.9x 105copy/μg for 88% of sensitivity and 94% of specificity. This cut off point is required to achieve HPV-16 DNA integration.(MOG 2013;21:77-83)

Keyword :

HPV-16, viral load, cervical cancer, -, -,


References :

Azis F,(2001) Masalah Kanker Serviks dan Upaya Penanganan Bandung : Pertemuan Forum Ilmiah Penelitian Kanker Serviks di Indonesia

Suwiyoga IK,(2000) Kanker Serviks: Evaluasi Faktor Risiko Klinis - : Majalah Obstetri Ginekologi Indonesia





Archive Article

Cover Media Content

Volume : 21 / No. : 2 / Pub. : 2013-05
  1. Radiotherapy Response Of Advanced Squamous And Adenocarcinoma Types Of Cervical Cancer At Dr Soetomo Hospital Surabaya
  2. Radiotherapy Outcome In Stage Iib Cervical Cancer Patients Resistant To Neoadjuvant Chemotherapy At Dr. Soetomo Hospital 2006 – 2010
  3. Correlation Between Risk Factors And Pelvic Organ Prolapse In Gynecology Outpatient Clinic, Dr. Soetomo Hospital Surabaya, 2007 – 2011
  4. Visualization Of Endometrial And Uterine Cavity Structure Abnormality With Transvaginal Sonography, Color Doppler Transvaginal Sonography And Saline Infusion Sonography In Abnormal Uterine Bleeding
  5. Expressions Of Growth Differentiation Factor-9 (gdf-9) Of Bovine Cumulus-oocyte Complex In Peritoneal Fluid Culture Of Infertile Patients With Endometriosis
  6. Viral Load Pada Kanker Serviks Terinfeksi Human Papilloma Virus Tipe 16
  7. Comparison Of Anti-mullerian Hormone (amh), Basal Follicle Stimulating Hormone (fsh), Estradiol And Antral Follicles Count As Predictors Of Ovarian Response In In Vitro Fertilization Program

Information MOG