Berkala Ilmiah Kimia Farmasi
ISSN 2302-8270
Vol. 4 / No. 2 / Published : 2015-11
Order : 1, and page :1 - 4
Related with : Scholar Yahoo! Bing
Original Article :
Perbandingan metode spektrofotometri sinar tampak dan titrasi kompleksometri untuk penentuan kadar zink dalam sediaan sirup
Author :
- FEBRI ANNURYANTI*1
- ASRI DARMAWATI*2
- JUNIAR MOECHTAR*3
- Dosen Fakultas Farmasi
- Dosen Fakultas Farmasi
- Dosen Fakultas Farmasi
Abstract :
Zink is an important micronutrient that can be used to supplement the therapy of diarrhea in children. To ensure the quality and effectiveness of zinc syrup, zinc determination has been done based on the intensity of the color of zinc-dithizone complex in acetone: propanol (1: 1) using visible spectrophotometer. Zinc concentrations are compared with complexometry method using EBT indicator. The concentration of zinc in samples using complexometry method was (106.1 ± 0.02)% of the amount listed on the label. Result of the zinc assay by complexometry method is more accurate than the result that obtained using visible spectrophotometer method.
Keyword :
zink syrup, visible light spectrophotometry, complexometry,
References :
Karpinska and M. Kulikowska,(2002) Simultaneous determination of zinc (II), manganese (II), and iron (II) in pharmaceutical preparations 29, p. 153-158. : Journal of Pharmaceutical and Biomedical Analysis
Archive Article
Cover Media | Content |
---|---|
![]() Volume : 4 / No. : 2 / Pub. : 2015-11 |
|