UNIVERSITAS AIRLANGGA



Detail Article

Folia Medica Indonesiana

ISSN 0303-7932

Vol. 48 / No. 4 / Published : 2012-10

Order : 9, and page :190 - 197

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Original Article :

Atomoxetine therapy effectiveness in children with adhd at day care, dr. soetomo hospital, surabaya

Author :

  1. Alviani Februana WP*1
  2. Yunias Setiawati*2
  3. Budiono*3
  1. Mahasiswa Fakultas Kedokteran
  2. Dosen Fakultas Kedokteran
  3. Dosen Fakultas Kedokteran

Abstract :

Attention Deficit Hyperactivity Disorder (ADHD) is a chronic psychiatry disorder, onset in childhood, with inattention, hyperactivity and impulsive syndrome within minimal two different social conditions, and usually diagnosed before seven years old. ADHD prevalence estimated between 3-7% school aged students. On Daycare RSU Dr. Soetomo, ADHD takes the second place the most case within these 5 years. Drug of choice used for ADHD is stimulant methylphenidate. Since its nontolerable side effects and growth retardation effect, nonstimulant atomoxetine is used as the alternative pharmacotherapy. In Indonesia, as far as writer knows, atomoxetine is either rarely used or observed. This observational analytical research aims to know the efficacy of atomoxetine in Daycare RSU Dr. Soetomo Surabaya by comparing the symptoms severity level before and after therapy. This research also compared the efficacy of atomoxetine between two types of ADHD found at Daycare. Total sampling assignment is used for ADHD patients and their parents who required the inclusion criteria (N: 42 inattention: 22 combined: 20). The data used is secondary data from Iowa Conner’s Rating Scale score assessed by parents, available on patient’s medical records, and primary data through the interview. Data analysis used statistical test. The results showed comparison of scores before and after therapy had p-value <0.0001. The difference of the severity of ADHD symptoms on the inattention and combined types showed differences p <0.05. Average change in scores on the ADHD combined type is larger than inattention type. In conclusion, atomoxetine therapy is effective in reducing severity level in ADHD patients at Daycare RSU Dr. Soetomo, and more effective for combined type patients than inattention type. (FMI 2012;48:190-197)

Keyword :

ADHD, Atomoxetine, Efficacy, Inattention Type, Combined Type,


References :

American Psychiatric Association,(2000) Diagnostic and Statistical Manual of Mental Disorders, 4th ed, Text Revision (DSM-IV-TR) Washington DC : American Psychiatric Association

Barkley RA,(1998) Attention Deficit Hyperactivity Disorder A Handbook for Diagnosis and Treatment, 2nd ed New York : The Guillford Press





Archive Article

Cover Media Content

Volume : 48 / No. : 4 / Pub. : 2012-10
  1. Antibacterial Activity Of Belimbing Wuluh (averrhoa Bilimbi Linn) Extract On Salmonella Typhi Growth
  2. Oral And Topical Aloe Vera Extract Administration In Diabetic Mice (mus Musculus) Wound Healing Process
  3. Effect Of Combined 500 Mg Vitamin C And 200 Iu Vitamin E On Plasma Malondialdehyde Level After Physical Exercise In Diving Athletes
  4. Antibacterial Activity Of Kunyit (curcuma Longa) Leaves Extract On Staphylococcus Aureus Examined Using Dilution Method
  5. Antibacterial Effect Of Strawberry (fragaria X Ananassa) Extract On Pathogenic Serotype 1-11 Escherichia Coli Revealed Using Dilution Method
  6. Guava (psidium Guajava L.) Juice Is Effective In Lowering Blood Glucose Level In Mice (mus Musculus)
  7. Clinical Profile Of Children With Steroid-sensitive Idiopathic Nephrotic Syndrome Relapsing In The First Year At Dr. Soetomo Hospital, Surabaya
  8. The Effects Of Soot Particulate Exposure On Tnf-α Expression In The Mechanism Of Cardiovascular Disorders
  9. Atomoxetine Therapy Effectiveness In Children With Adhd At Day Care, Dr. Soetomo Hospital, Surabaya
  10. Sweet Star Fruit Reduces Blood Pressure In Normotensive Subjects

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