Folia Medica Indonesiana
ISSN 0303-7932
Vol. 50 / No. 1 / Published : 2014-01
Order : 4, and page :15 - 18
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Original Article :
Er, pr, and her-2/neu profile on young breast carcinoma patients
Author :
- Caesarisma Vidiyanti*1
- Dyah Fauziah*2
- Desak Gede Agung Suprabawati*3
- Mahasiswa Fakultas Kedokteran
- Dosen Fakultas Kedokteran
- Dosen Fakultas Kedokteran
Abstract :
Breast carcinoma is one of the most common malignancy in women with increasing incidence rate every year. Evidence stronglysuggested the cancer tends to occur at younger age. The aim of this study is to observe the characteristic of estrogen receptor (ER),progesterone receptor (PR), and HER-2/neu in young female breast carcinoma patient during 2010. ER, PR and HER-2/neu statuswere obtained from Pathology Anatomy Department Faculty of Medicine Airlangga University/Dr. Soetomo Hospital medicalrecords throughout 2010, with related data documented. From the medical records, only breast carcinoma with available ER, PRand HER-2/neu status with age of patient less or equal to 35 years old were taken as samples. From 21 cases, the age ranged from26 to 35 years old, with median of 32 years old and the most common age was 35 years old. ER status was positive in 42.86%samples, PR status was positive in 19.05% samples and HER-2/neu expression was positive on 33.34% samples. Most patient havenegative ER status, negative PR status, and negative HER-2/neu expression. Further examination with fluorescence in situhybridization (FISH) is required. (FMI 2014;50:15-18)
Keyword :
breast carcinoma, estrogen receptor, progesterone receptor, HER-2/neu,
References :
Avis NE, Crawford S, Manuel J,(2005) Quality of life among younger women with breast cancer - : J Clin Oncol
Fisher ER, Redmond CK, Liu H, Rockette H, Fisher B,(1980) Correlation of estrogen receptor and pathologic characteristics of invasive breast cancer - : Cancer
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