UNIVERSITAS AIRLANGGA



Detail Article

Folia Medica Indonesiana

ISSN 0303-7932

Vol. 49 / No. 1 / Published : 2013-01

Order : 1, and page :1 - 7

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Original Article :

The effect of emotional quality management on cortisol, tnf-, and il-2 in women with breast cancer

Author :

  1. Padoli*1
  1. Health Polytechnique, Ministry of Health Surabaya

Abstract :

Women with breast cancer are often diagnosed of having emotional and psychosocial problems. This distress can influence immune system, and may be decreasing individual’s ability to fight the disease and metastasis. Emotional Quality Management (EQM) model is strategy with a focus to increase emotional maturity. Emotional maturity will lead to positive perception of women with breast cancer. The objective of this study was to find the effect of EQM training on immunity responses that were measured with cortisol, tumor necrosing factor alpha (TNF-a), interleukin-2 (IL-2) and interferon gamma in women with breast cancers. Twenty-eight women with breast cancer undergoing chemotherapy in Dr Soetomo hospital outpatient clinic were selected and divided into two groups. First group was given with EQM training four times and the second group served as control. Peripheral blood sample was used to measure immune responses: cortisol, TNF-a and IL-2. Results obtained from each group were analyzed using analysis of variance with T test. This study demonstrated that EQM training for women with breast cancer had significantly lowered cortisol level. No differences between the groups were seen for TNF-a and IL-2 levels. In conclusion, Emotional Quality Management improved perception of stress modulate the activity of the HPA axis, resulting in decreased cortisol levels, followed by a trend of increased TNF-a, and IL-2. These cytokines are indicators of improved cellular immunity that is necessary for the patient’s body resistance against breast cancer cells. (FMI 2013;49:1-7)

Keyword :

Emotional Quality Management, cortisol, TNF-, IL-2,


References :

Ader R,(2007) Psychoneuroimmunology, 4th ed. New York : Elsevier

Ah DV and Kang DH,(2009) Significant impairment in immune recovery following cancer treatment - : Nurs Res. 58





Archive Article

Cover Media Content

Volume : 49 / No. : 1 / Pub. : 2013-01
  1. The Effect Of Emotional Quality Management On Cortisol, Tnf-, And Il-2 In Women With Breast Cancer
  2. Reduced Addiction In Drugs Abusers Undergoing Dhikr At Ponpes Inabah Xix Surabaya
  3. Induced Abortion At Midgestation Of Sheep By Stress
  4. Polymerase Chain Reaction Of Mycobacterium Tuberculosis Gyrb Gene Region For Rapid Screening Test Of Pulmonary Tuberculosis
  5. Muscle Glucose Transporter 1 (glut-1) Expression In Diabetic Rat Models
  6. Characterization Of Fertilin Beta Protein Of Human Sperm Membrane. A Candidate For Immunocontraception
  7. Il-2 Level In Diabetic Mice Due To Obesity Is Higher Than That In Healthy Mice
  8. Supportive Pediatric Programs At Kampai Tabu Karambia Community Health Center Towards Mdgs 2015
  9. Correlation Between Superoxide Dismutase Serum And Sensoryneural Hearing Disorder In Patients With Multi Drug Resistance Tuberculosis
  10. Ethanol Extract From Petiveria Alliacea (singolawang) Inhibits The Growth Of Mycobacterium Tuberculosis In Vitro
  11. Acceleration Of Desa Siaga Aktif In Subdistrict Bareng, Jombang, 2012
  12. Effect Of Rimpang Temu Giring (curcuma Heyneana Val. & V. Zijp.) And Rimpang Temu Hitam (curcuma Aeruginosa Roxb.) Boiled Water On The Mortality Of Fasciola Hepatica Worm In Vitro
  13. Cytological Diagnostic Accuracy In Skin Tumor

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