Jurnal Ilmiah Biologi FST
ISSN 2303-3428
Vol. 1 / No. 1 / Published : 2013-01
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Original Article :
Pengaruh penggunaan matras elektromagnetik terhadap toleransi glukosa pada tikus putih (rattus novergicus) diabetik tipe ii
Author :
- Dwi Winarni*1
- Suhariningsih*2
- I.B. Rai Pidada*3
- Dwi Esti Ayu Rosandria*4
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Abstract :
This study aimed to evaluate the effect of electromagnetic mattress with various frequency of electric field generator in glucose tolerance test of type 2 diabetic rats (Rattus novergicus). Type 2 diabetes was induced by intra-peritoneal injection (i.p.) of streptozotocin (STZ) at a dose of 100 mg / kg bw i.p., 15 minute before the intra-peritoneal administration of nicotinamide (240 mg / kg bw, i.p.). Rats were divided into 2 groups which first group was 12 rats in control group (K) without induced by STZ and the other was 16 diabetic rats in treatment group (D). These groups were divided further into subgroups. Control group had subgroups K15, K30, K60 and diabetic group had subgroups D15, D30, D60, and D0. Fifteen, 30, and 60 denoted the frequency was used in this study, with 0 for treatment without mattress. Mattress treatment was given everyday for one hour until 28 days. Glucose tolerance test was done at day 28, by giving D-glucose (2 g / kg bw, p.o.) orally to 12 hours fasted rats after that measured blood glucose levels at 0, 30, 60, 90, and 120 minutes. The result of this study showed that use of electromagnetic mattress could reduce blood glucose levels but couldn’t improve tolerance of cell to glucose.
Keyword :
diabetes mellitus, streptozotocin, Rattus novergicus, glucose tolerance test, electromagnetic mattress,
References :
Arora, S., Ojham S. K., dan Vohora, D.,(2009) Characterisation of streptozotocin Induced Diabetes Mellitus in Swiss Albino Mice - : Global Journal of Pharmacology, 3 (2) : 81-84
Cartee, G. D., dan Funai, K.,(2009) Regulation and Roles of AS160 and TBC1D1 for Glucose Transport by Skeletal Muscle - : http://www.medscape.com/viewarticle/709988_4
Firdous, M., Koneri, R., Sarvaraidu, C. H., Harish, M., dan Shubhapriya, K. H.,(2009) NIDDM Antidiabetic Activity of Saponins of Momordica cymbalaria In Streptozotocin-Nicotinamide Mice - : Journal of Clinical and Diagnostic Research, 3: 1460-1465
Jamieson I.A., dan Holdstock P.,(2010) Electromagnetic Phenomena and Health: A Continuing Controversy - : J IOP Conf. Ser.: Earth Environ.Sci, 10: 1088-1315
Kaur, S., dan Kapil, U.,(2010) Impaired Glucose Tolerance and Diabetes Mellitus in Obese Children - : Indian Pediatrics of Medical Science, 47: 362-364
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