UNIVERSITAS AIRLANGGA



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ISSN 1858-3598

Vol. 7 / No. 1 / Published : 2012-04

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Original Article :

Respons psikologis (kecemasan dan depresi) dan respons biologis (cortisol, ifn-γ dan tnf-α) pada pasien stroke iskemik dengan pendekatan model home care holistic (psychological respons (anxiety and depression) and biological respons (cortisol, ifn-γ and tnf-α) in ischemic stroke patients by home care holistic model approach)

Author :

  1. Luluk Widarti*1
  2. Moh. Hasan Mahfoed*2
  3. Kuntoro*3
  4. I Ketut Sudiana*4
  1. Poltekes Kemenkes RI Surabaya
  2. Ilmu Penyakit Saraf Fakultas Kedokteran Universitas Airlangga
  3. Fakultas Kesehatan Masyarakat Universitas Airlangga
  4. Fakultas Kedokteran Universitas Airlangga

Abstract :

Introduction: Stroke has become the major causes of the diseases for long-term disability. The patient with stroke often experience on psychological disorder such as anxiety and depression that lead to biologycal aspects such as on cytokin. The objective of the study was to analyse the corelation between psychological respons (anxiety and depression) and biological respons (cortisol, ifn-γ dan tnf-α) in ischemic stroke patients by home care holistic model approach. Methods: This study applied aAn experimental research with quasy experimental design specifically nonrandomized pre-test post-test control group design was applied in this study. The Study was conducted in the area of Surabaya by selecting ischemic stroke patients after being hospitalized at ”A-Seruni room, Medic IRNA, Dr. Soetomo hospital”. A sample of size 40 was patients divided equally into two groups, control and treatment groups. The treatment and control groups respectively received holistic home care and home care. The depression and anxiety level were measured by using questionnaires and observation technique, while  Cortisol level, IFN-γ and TNF-α levels were measured by using ELISA quantitative technique. The data was analyzed by using Levene’s test for homogeneity of variance, T-test and correlation test. Result: The statistical analysis shows there was a significant difference between psychological response in control group after intervension with p = 0,000 for anxiety, and p= 0,000 for depression. For biological response, there is a significant difference p= 0,007 for cortisol and p= 0,000 for TNF-α. However, there is no significant difference in IFN-γ with p = 0,425. The correlation test result shows there was significant correlations between anxiety and biological responses such as Cortisol with r= 0,724 and p= 0,038; IFN- γ with r= 0,475 and p= 0,034;  TNF- α with r = 0,592 and p= 0.006. Furthermore, there was positive correlation between depression and biological responses such as Cortisol with r= 0,705 and p= 0.033;  IFN- γ  with r= 0,454 and p= 0.044,   TNF-α  with r = 0,561 and p= 0.010. Discussion: Holistic home care could improve the psychological responses by decreasing anxiety and depression level and also could improve biological responses by decreasing Cortisol, IFN-γ and TNF-α level in ischemic stroke patients. It is recommended to make standard operational procedure of holistic home care that can be implemented by all health person who take care ischemic stroke patients.

Keyword :

Holistic Home Care, Anxiety and Depression, Biological Responses,


References :

Diwanto, M., A.,(2009) Tips Mencegah Stroke, Hipertensi dan Serangan Jantung Yogyakarta : Paradigma Indonesia

Depkes RI.,(2002) Pedoman Perawatan Kesehatan di Rumah Jakarta : Direktorat Keperawatan dan keteknisian Dirjen Yanmed





Archive Article

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Volume : 7 / No. : 1 / Pub. : 2012-04
  1. Respons Psikologis (kecemasan Dan Depresi) Dan Respons Biologis (cortisol, Ifn-γ Dan Tnf-α) Pada Pasien Stroke Iskemik Dengan Pendekatan Model Home Care Holistic (psychological Respons (anxiety And Depression) And Biological Respons (cortisol, Ifn-γ And Tnf-α) In Ischemic Stroke Patients By Home Care Holistic Model Approach)
  2. Peningkatan Self-care Agency Pasien Dengan Stroke Iskemik Setelah Penerapan Self-care Regulation Model (the Improvement Of The Self-care Agency For Patients With Ischemic Stroke After Applying Self–care Regulation Model In Nursing Care)
  3. Tingkat Kepatuhan Pasien Gagal Ginjal Kronik Dalam Pembatasan Cairan Pada Terapi Hemodialisa (the Compliance Chronic Renal Failure Patient On Restrictions Liquids In Hemodialysis Therapy)
  4. Konsep Diri, Dukungan Sosial Dan Kecemasan Menghadapi Keadaan Sakit Pada Pasien Fraktur (self-concept, Social Support, And Anxiety In Dealing With Fractured-patient)
  5. Faktor Risiko Timbulnya Diabetes Mellitus Pada Remaja Smu Di Kota Malang The Risk Factors Of Diabetes Mellitus In Adolescent High School In Malang City
  6. Mutu Asuhan Keperawatan Berdasarkan Analisis Kinerja Perawat Dan Kepuasan Perawat Dan Pasien (quality Of Nursing Care Based On Analysis Of Nursing Performance And Nurse And Patient Satisfaction)
  7. Model Adaptif Conservation (acm) Dalam Meningkatkan Dukungan Keluarga Dan Kepatuhan Berobat Pada Pasien Tb Paru Di Wilayah Kota Surabaya (adaptif Conservation (acm) Model In Increasing Family Support And Compliance Treatment In Patient With Pulonary Tuberculosis In Surabaya City Region)
  8. Pengembangan Model Peningkatan Kinerja Tenaga Keperawatan Dalam Penerapan Manajemen Terpadu Balita Sakit (mtbs) Di Surabaya (the Development Of Nursing Job Performance Model In The Implementation Of Integrated Management Of Childhood Illness (imci) In Surabaya)
  9. Peningkatan Kebersihan Diri Pada Pasien Halusinasi Dengan Pendekatan Metode Partisipatif Dan Rewards (the Increase Of Self Personal Hygiene Patient With Hallusination By Nursing Methods Of Partisipatif And Rewards Approach)
  10. Ekspresi Protein Er (estrogen Receptor) Pada Kanker Payudara Derajat Keganasan Baik, Sedang Dan Buruk (protein Expression Er (estrogen Receptor) In Breast Cancer Degree Of Malignancy Low, Moderate, Severe)
  11. The Increasing Of Preschool Multiple Intelligences By Educative Playing Instrument Stimulation

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